Sökning: "ETB receptor"

Visar resultat 1 - 5 av 32 avhandlingar innehållade orden ETB receptor.

1. 1. Vascular Endothelin and Angiotensin Receptors Regulation in Inflammatory Arterial Disorders

   Författare :Ivan Dimitrijevic; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ischemic heart disease; resistance artery; giant cell arteritis; temporal artery; immunohistochemistry; AT2 receptor; AT1 receptor; Endothelin-1; ETA receptor; ETB receptor;

   Sammanfattning : The present thesis is aimed to examine the hypothesis that the degree of vascular inflammation correlates with the expression of vascular endothelin and angiotensin receptors. The receptor changes were studied in subcutaneous resistance arteries in patients with different degrees of ischemic heart disease (IHD). LÄS MER

3. 2. Endothelin receptor changes during inflammation in the lung

   Författare :Bengt Granström; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; Upregulation; Smooth muscle cells; Smoking; Sephadex; Remodeling; Rat; mRNA; Human; ETB receptor; ETA receptor; Lung; Endothelin; Asthma bronchiale; Contraction;

   Sammanfattning : Endothelin-1 (ET-1) is an extremely potent smooth muscle spasmogen well known from the vascular system but also active within the airways. The importance of its proinflammatory and co-mitogenic properties has become increasingly evident, the endothelin system also having been shown to mimic the signal features of asthma, COPD and other pulmonary diseases. LÄS MER

4. 3. Receptor Upregulation and MAPK Activity in Arteries and Bronchi Following Secondhand Smoke Exposure

   Författare :Lei Cao; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coronary arteries; cerebral arteries; 5-hydroxytryptamine receptor; endothelin receptor; secondhand smoke exposure; bronchi;

   Sammanfattning : Cigarette smoking is a major risk factor for cardiovascular and respiratory diseases. Contractile receptor changes have been observed in several vascular diseases. The intracellular mitogen activated protein kinase (MAPK) signaling pathways are suggested to be associated with receptor upregulation. LÄS MER

5. 4. Vascular receptor changes in ischemic stroke

   Författare :Emelie Stenman; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vascular receptor changes; Ischemic stroke; Endothelin; Angiotensin; Cardiovascular system; Kardiovaskulära systemet; Pharmacological sciences; pharmacognosy; pharmacy; farmakognosi; farmaci; toxikologi; toxicology; Farmakologi;

   Sammanfattning : The present thesis aimed to examine how ischemic stroke affects the vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. LÄS MER

7. 5. Neurohormonal Modulators in the Parathyroid Gland. Localization and regulation

   Författare :Lena Luts; Malmö Patologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Receptor; In situ hybridization; Immunocytochemistry; Nitric Oxide Synthase; Endothelin; Neuropeptides; Chromogranin; Parathyroid adenoma; Parathyroid gland; Parathyroid hormone; mRNA; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

   Sammanfattning : The occurrence and distribution of neurohormonal peptides, neuroendocrine markers and receptors in parathyroid nerve fibers and endocrine cells are described, using immunocytochemistry, in situ hybridization, image analysis and reverse transcriptase polymerase chain reaction. Immunocytochemical studies revealed that parathyroid glands of chicken, rat, guinea-pig, cat, dog and sheep contained adrenergic-, cholinergic-, and peptide-containing nerve fibers. LÄS MER