Sökning: "transcriptional switch"

Visar resultat 11 - 15 av 59 avhandlingar innehållade orden transcriptional switch.

  1. 11. Heterobasidion - conifer pathosystem : heterologous array analysis and transcriptional shift from saprotrophic to necrotrophic growth

    Författare :Karl Lundén; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : In this thesis the Heterobasidion – conifer pathosystem is discussed in a symbiosis context. Heterobasidion annosum (Fr.)Bref. s. LÄS MER

  3. 12. Macromolecular Matchmaking : Mechanisms and Biology of Bacterial Small RNAs

    Författare :Erik Holmqvist; E. Gerhart H. Wagner; Udo Bläsi; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Small RNA; sRNA; non-coding RNA; antisense; gene regulation; post-transcriptional regulation; translational control; outer membrane protein; OmpA; MicA; biofilm; flagella; curli; bistability; Lrp; MicF; CsgD; FlgM; OmrA; OmrB; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : Cells sense the properties of the surrounding environment and convert this information into changes in gene expression. Bacteria are, in contrast to many multi-cellular eukaryotes, remarkable in their ability to cope with rapid environmental changes and to endure harsh and extreme milieus. LÄS MER

  4. 13. The interplay of transcription and chromatin regulation during embryonic development

    Författare :George Hunt; Mattias Mannervik; Eileen Furlong; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; transcription; chromatin; chromatin-modifiers; p300 CBP; Polycomb repression; promoter proximal Pol II pausing; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : A fascinating aspect of multicellular development is the production of diverse cell types from an identical DNA genome, which depends on the ability to express different complements of genes across space and time. This thesis tries to address how the genome, within the chromatin structure that envelops it, is regulated to direct this complex process. LÄS MER

  5. 14. Immunoglobulin isotype switching in health and disease

    Författare :Berivan Baskin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Immunoglobulin isotype switching is the process where the Cmy region, initially located downstream of the VDJ region is replaced by another constant region gene. Class switch recombination takes place between switch (S) regions, composed of tandem repeats of short unit sequences, located 5 of each CH gene, except for Cdelta. LÄS MER

  7. 15. The hematopoietic transcription factor RUNX1 : a structural view

    Författare :Stefan Bäckström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; RUNX1; Runt domain; CBFβ; transcription factor; leukaemia; protein crystallography; anomalous diffraction; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; molekylärbiologi; Molecular Biology;

    Sammanfattning : The malfunction of the transcriptional regulator RUNX1 is the major cause of several variants of acute human leukemias and its normal function is to regulate the development of the blood system in concert with other transcriptional co-regulators. RUNX1 belongs to a conserved family of heterodimeric transcription factors that share a conserved DNA binding domain, the Runt domain (RD), named after the first member of this group – Runt - found in Drosophila melanogaster. LÄS MER