Sökning: "early-life microbial exposure"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden early-life microbial exposure.
1. Microbial and maternal influences on allergic sensitization during childhood: defining a role for monocytes
Sammanfattning : Allergic diseases are influenced by genetics and the environment. Maternal allergy appears to confer a higher risk for allergic sensitization than paternal allergy, suggesting an in utero influence. LÄS MER
2. The Gut Bacterial Flora - Focus on Early Life and Physiological Traits
Sammanfattning : The gastrointestinal tract of the foetus is considered sterile but during vaginal birth the neonate comes into contact with bacteria from the maternal vaginal and intestinal microbiota. The main focus of this doctoral thesis was to elucidate the initial bacterial ecosystem in newborns and to relate microbial perturbations to physiological traits. LÄS MER
3. Early-life gut microbiota and breast milk oligosaccharides in relation to childhood immune maturation and allergy
Sammanfattning : Atopic allergy is the most common chronic disease among children in the developed world. This high prevalence could be associated with low microbial exposure. The early gut microbiota appears to be important for immune maturation. LÄS MER
4. Pregnancy—A Critical Time for Mental Health : Interrogating Psychiatry with Microbiota-Gut-Brain Axis and Autonomic Nervous System Biomarkers
Sammanfattning : Perinatal mood and anxiety disorders (PMADs) are common and impact the parent and child beyond the perinatal period of pregnancy and postpartum. The aim of this thesis was to study biomarkers that might reflect perinatal mental health. LÄS MER
5. Understanding allergies : how infections affect the function of T helper cells
Sammanfattning : Allergic disorders are caused by a combination of hereditary and environmental factors. The hygiene hypothesis postulates that early-life microbial exposures impede the development of subsequent allergic diseases. However, unambiguous evidence that microbes reduce the development of allergic disorders is still lacking. LÄS MER