Sökning: "toll like receptor"
Visar resultat 1 - 5 av 100 avhandlingar innehållade orden toll like receptor.
1. Toll-like receptors (TLRs) and inflammatory bone modeling
Detta är en avhandling från Umeå : Umeå UniversitySammanfattning : Patients with inflammatory or infectious conditions such as periodontitis, peri-implantitis, osteomyelitis, rheumatoid arthritis, septic arthritis and loosened joint prosthesis display varying severity of destruction in the adjacent bone tissue. Bone loss in inflammatory diseases is considered a consequence of cytokine induced RANKL and subsequent enhanced osteoclast formation. LÄS MER
2. Developing brain and systemic inflammation: a "Toll-like" link with consequences
Detta är en avhandling från Umeå : Umeå UniversitySammanfattning : The developing brain is vulnerable to external insults, and perinatal brain injury (PBI) is a major cause of life-long neurological syndromes such as cerebral palsy. Currently, no pharmaceutical intervention is available. Hypoxia/ischemia (HI), infections and inflammation are implicated in the pathogenesis of PBI. LÄS MER
3. Toll-like receptor activation induced changes in dendritic cells
Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Medicine, HuddingeSammanfattning : Dendritic cells (DC) are professional antigen-presenting cells that act as a “bridge” between innate and adaptive immunity by the induction and subsequent orchestration of immune responses. The ligation of Toll-like receptors (TLR) and other innate receptors on DC determines their immune-stimulating capacity. LÄS MER
4. Role of Toll-like receptors in airway inflammation
Detta är en avhandling från Department of Otorhinolaryngology, Lund UniversitySammanfattning : Toll-like receptors (TLRs) are germline-encoded pathogen-recognition receptors that detect different microbial structures and activate the immune system. The human TLR family presently comprises ten members (TLR1-TLR10), each with distinct properties. LÄS MER
5. The role and mechanism of ubiquitin system in innate immune regulation
Detta är en avhandling från Umeå : Umeå UniversitySammanfattning : Pattern-recognition receptors (PRRs) include the cell surface or endosomal membrane localized Toll-like receptors (TLRs) and the cytoplasmic PRRs such as RIG-I-like receptors (RLRs), NOD-like receptors (NLRs) and cytoplasmic DNA receptors (CDRs). Triggering of PRRs culminates in the transcriptional induction of pro-inflammatory cytokines and type I interferons (IFNs) that coordinate protection against pathogens but require tight control to avert inflammatory diseases. LÄS MER
