Sökning: "maternal allergy"
Visar resultat 1 - 5 av 45 avhandlingar innehållade orden maternal allergy.
1. Long chain polyunsaturated fatty acids in serum phospholipids - relation to genetic polymorphisms, diet and allergy development in children
Sammanfattning : Polyunsaturated fatty acids (PUFAs) are essential for human cell and tissue development. In foetus, PUFAs are supplied via placental transfer from maternal circulation. After birth, PUFAs are supplied via the diet. Long chain PUFAs (LCPUFAs) may also be synthesized from precursor fatty acids present in the diet. LÄS MER
2. Diet and dietary biomarkers during pregnancy and lactation in relation to offspring allergy development
Sammanfattning : Allergy causes a large burden on society and reduces the quality of life for the individual. The increased allergy incidence over the last decades cannot be explained by genetics. Research has indicated that diet, which is a modifiable factor, might influence the risk of developing allergy. LÄS MER
3. Maternal and neonatal metabolomes and their associations to immune maturation and allergy in early life
Sammanfattning : Allergy, one of the most common chronic diseases worldwide, is caused by a dysregulated immune system reacting to normally harmless proteins. However, regulating mechanisms are not well understood. The aim of this thesis was to investigate if plasma and placenta metabolites associate prospectively to allergy development and immune maturation. LÄS MER
4. Cytokine studies in the generation and treatment of IgE-mediated allergy
Sammanfattning : So called Th2 cytokines, such as IL-4 and IL-13 are responsible for the formation of IgE antibodies, the effector antibody in atopic allergy. Cytokines of Th1 type, for example IFN-g, inhibit these responses. This thesis describes work aimed at elucidating the cytokine production underlying IgE-mediated allergy. LÄS MER
5. Early dietary exposure is associated with allergy development in the FARMFLORA birth cohort
Sammanfattning : The allergy prevalence is markedly low in children growing up on farms. Contact with livestock and consumption of unpasteurized milk has been associated with allergy protection, although other elements in the environment may contribute. LÄS MER