Sökning: "systemic disease"

Visar resultat 11 - 15 av 718 avhandlingar innehållade orden systemic disease.

  1. 11. Genetic Characterization of Chicken Models for Autoimmune Disease

    Författare :Anna-Stina Sahlqvist; Olov Ekwall; Olle Kämpe; Leif Andersson; Susanne Kerje; Holger Luthman; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Autoimmune disease; Hashimoto’s thyroiditis; systemic sclerosis; comparative genomics; linkage analysis; OS chickens; spontaneous autoimmune thyroiditis; UCD-200 chickens.; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Autoimmune diseases are endemic, but the disease mechanisms are poorly understood. A way to better understand these are to find disease-regulating genes. However, this is difficult as the diseases are complex, with several genes as well as environmental factors influencing the development of disease. LÄS MER

  3. 12. Murine Systemic Lupus erythematosus : cellular regulation and molecular mechanisms behind the formation of autoantibodies in autoimmune disease

    Författare :Marta E. Alarcón-Riquelme; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cytologi; Cellbiologi; Immunologi;

    Sammanfattning : .... LÄS MER

  4. 13. Systemic sclerosis. Novel molecular and epidemiological features of disease

    Författare :Kristofer Andréasson; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic sclerosis; fibrosis; COMP; calprotectin; biomarker; gastrointestinal;

    Sammanfattning : Systemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. LÄS MER

  5. 14. Studies on the Associations between Dental Caries, Periodontal Disease and Different Systemic Conditions

    Författare :Hani T Fadel; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipokines; coronary artery disease; dental caries; obesity; periodontal disease; psoriasis; risk assessment;

    Sammanfattning : Background and aims: Dental caries and periodontal disease are the two most common oral diseases in man. Evidence shows that they may be directly or indirectly related to each other and to other systemic conditions. LÄS MER

  7. 15. Genetic Risk Factors for Systemic Lupus Erythematosus : From Candidate Genes to Functional Variants

    Författare :Anna-Karin Abelson; Marta Alarcón-Riquelme; Holger Luthman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic Lupus Erythematosus; SLE; association study; complex disease; genetic; Medical genetics; Medicinsk genetik;

    Sammanfattning : The aim of this thesis has been to identify genetic variants that increase the susceptibility for Systemic Lupus Erythematosus (SLE), an autoimmune disease caused by a complex interplay between various genetic and environmental factors. Five different candidate genes were selected through different strategies, and were analysed for association with SLE in an attempt to distinguish some of the underlying mechanisms of this disease. LÄS MER