Sökning: "systemic disease"

Visar resultat 16 - 20 av 718 avhandlingar innehållade orden systemic disease.

1. 16. Genetic Mapping of Susceptibility Genes for Systemic Lupus Erythematosus

   Författare :Bo Johanneson; Jean Pierre Hugot; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Association analysis; Candidate gene; Complex disease; Genome scan; Linkage analysis; Mapping; Susceptibility genes; Systemic lupus erythematosus; Genetik; Genetics; Genetik; medicinsk genetik; Medical Genetics;

   Sammanfattning : Systemic lupus erythematosus (SLE) is a complex autoimmune disease with unknown etiology. The aim of this thesis was to identify susceptibility regions through genetic mapping, using model-based linkage analysis on nuclear and extended SLE multicase families. LÄS MER

3. 17. Nutritional Depletion in Chronic Obstructive Pulmonary Disease (COPD) : Effect on Morbidity, Mortality and Physical Capacity

   Författare :Runa Hallin; Christer Janson; Frode Slinde; Magnus Sköld; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic obstructive pulmonary disease; nutrition; pulmonary rehabilitation; physical capasity; systemic inflammation; Lung diseases; Lungsjukdomar;

   Sammanfattning : The overall aim of this work was to examine the effects of depleted nutritional status on some aspects of Chronic Obstructive Pulmonary Disease (COPD).Morbidity. In paper І, we found that energy intake was lower than the calculated energy demand for all patients. LÄS MER

4. 18. On inflammation and cardiovascular disease in patients with rheumatoid arthritis

   Författare :Solveig Wållberg Jonsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; mortality; cardiovascular disease; ischemic heart disease; inflammation; lipids; Lp a ; haemostasis; fibrinolysis; atherogenesis; thrombogenesis;

   Sammanfattning : Patients with rheumatoid arthritis (RA) have a shorter life span than the general population. An increased death due to cardiovascular disease (CVD) has been reported. RA is characterized by synovitis and joint destruction accompanied by an acute phase reaction and systemic features. LÄS MER

5. 19. Genetic Contributions to Manifestations and Prognosis of Systemic Lupus Erythematosus

   Författare :Sarah Reid; Dag Leonard; Timothy Niewold; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic lupus erythematosus; genetics; cardiovascular disease; polygenic risk score; smoking; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Systemic lupus erythematosus (SLE) is a severe autoimmune disease with a multifactorial aetiology and an extremely heterogenous clinical picture. This thesis explores the impact of SLE genetic variants, through their cumulative effect or gene-environment interactions, on SLE manifestations and complications. LÄS MER

7. 20. Peri-implantitis and periodontitis. Experimental and clinical studies

   Författare :Olivier Carcuac; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dental implant; animal experiment; biopsy; radiology; histology; immunohistochemistry; inflammation; peri-implant disease; periodontal disease; treatment; systemic antibiotics; antiseptics;

   Sammanfattning : Peri-implantitis is an increasing problem in implant dentistry. The current series of studies employed a translational approach with the aim to compare peri-implantitis and periodontitis lesions and evaluate the influence of implant surface characteristics and the adjunctive use of systemic antibiotics/local antiseptics on healing following surgical treatment of peri-implantitis. LÄS MER