Sökning: "Olle Kämpe"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Olle Kämpe.

  1. 1. Functional properties of transplantation antigens

    Författare :Olle Kämpe; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 2. Immunological Studies using Human and Canine Model Disorders

    Författare :Kerstin M. Ahlgren; Anna Lobell; Olle Kämpe; Kerstin Lindblad-Toh; Roland Jonsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoimmunity; T cell; T helper cell; B cell; Autoantibodies; Interferon; Interleukin; Dogs; APS-1; Candida albicans; fungus; Immunologi; Immunology; Medicin; Medicine;

    Sammanfattning : The studies presented in this thesis focus on human and canine models for autoimmune disease, with the main aim to gain new knowledge about disease mechanisms and to further evaluate the dog as a model for autoimmune disease. Autoimmune Polyendocrine Syndrome type 1 (APS-1) is a hereditary human multiorgan disease caused by mutations in the autoimmune regulator (AIRE) gene. LÄS MER

  4. 3. Molecular Targets in Autoimmune Polyendocrine Syndrome Type1 and Their Clinical Implications

    Författare :Mohammad Alimohammadi; Olle Kämpe; Anna Lobell; Fredrik Rorsman; Tommy Olsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoimmunity; autoantibodies; endocrinology; parathyroid; hypoparathyroidism; Addison s disease; pulmonary symptoms; NALP; NALP5; NLR; KCNRG; Molecular medicine; Molekylär medicin;

    Sammanfattning : Autoimmune diseases occur when the immune system attacks and destroys healthy body tissue. Autoimmunity is known to cause a wide range of disorders, and is suspected to be responsible for many more. Most autoimmune disorders are chronic and cause severe morbidity for the patients, and are also costly for society. LÄS MER

  5. 4. Autoantigens in Inflammatory Bowel Disease and Primary Sclerosing Cholangitis

    Författare :Brita Ardesjö; Olov Ekwall; Olle Kämpe; Fredrik Rorsman; Eric Gershwin; Uppsala universitet; []
    Nyckelord :Molecular medicine; inflammatory bowel disease; primary sclerosing cholangitis; autoimmunity; autoantigen; goblet cell; Molekylärmedicin;

    Sammanfattning : Inflammatory bowel disease (IBD) comprises diseases that are characterized by chronic or relapsing inflammation of the gastrointestinal tract. Primary sclerosing cholangitis (PSC) is an extraintestinal manifestation in IBD. LÄS MER

  7. 5. Model diseases for studies of autoimmunity

    Författare :Frida Dalin; Mohammad Alimohammadi; Olle Kämpe; Sophie Bensing; Lucia Mincheva-Nilsson; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : The events triggering autoimmune diseases are to large extent unknown and model diseases are an important tool in studies aiming to elucidate molecular mechanisms in autoimmunity. Autoimmune Addison’s disease (AAD) is a rare disease characterized by autoimmune destruction of adrenal glands and most patients with AAD have autoantibodies against the enzyme 21‑hydroxylase in the adrenal cortex. LÄS MER