Sökning: "stopped-flow spectroscopy"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden stopped-flow spectroscopy.
1. Effects of Macromolecular Crowding on Protein Folding : - in-vitro equilibrium and kinetic studies on selected model systems
Sammanfattning : Protein folding is the process during which an extended and unstructured polypeptide converts to its compact folded structure that is most often the functional state. The process has been characterized extensively in dilute buffer in-vitro during the last decades but the actual biological place for this process is the inside of living cells. LÄS MER
2. Formation and Decomposition of Platinum–Thallium Bond, Kinetics and Mechanism. Structural Characterization of Some Metal Cyanides in the Solid State
Sammanfattning : The kinetic and mechanistic features of a new series ofplatinum-thallium cyano compounds containing a direct andunsupported by ligands metal-metal bond have been studied insolution, using standard mixandmeasurespectrophotometric technique and stoppedflow method.These reactions are interpreted as oxidative addition of the cspecies to the square planar Pt(CN)42-complex. LÄS MER
3. Diffusive interactions play an important role in protein stability and mobility : Investigations of the intracellular milieu using in-cell NMR
Sammanfattning : Proteins are crucial for all cellular life. Every signal received by a cell, and every response to it, is mediated by proteins. Inside cells, these proteins diffusively sample each other’s surfaces, as they travel through the cytoplasm in search of their specific interaction partners. LÄS MER
4. Structure-Reactivity Correlations for Reactions of Palladium(II) and Platinum(IV) Complexes
Sammanfattning : The kinetics and mechanism for substitution reactions on tetraaquapalladium(II) by an extended series of thioethers, a great number of carboxylic acids, and olefins have been studied by use of UV-VIS, stopped-flow, and high-pressure stopped-flow spectrophotometry and NMR spectroscopy. Second-order rate constants k and activation parameters (activation enthalpies, entropies, and volumes) for formation of monodentate 1:1 complexes have been determined. LÄS MER
5. Characterization of two novel fatty acid dioxygenases : Linoleate diol synthase and manganese lipoxygenase
Sammanfattning : Two classes of fatty acid dioxygenases, PGH synthases (hemeproteins) and lipoxygenases (non-heme iron proteins), are of eminent pharmacological importance. This thesis describes a PGH synthase-related dioxygenase designated linoleate diol synthase (LDS) and the first native occurring manganese-containing lipoxygenase. LÄS MER