Sökning: "splicing"

Visar resultat 11 - 15 av 236 avhandlingar innehållade ordet splicing.

  1. 11. The regulation of incorrect splicing of ISCU in hereditary myopathy with lactic acidosis

    Författare :Denise F. R. Rawcliffe; Monica Holmberg; Helena Edlund; Diana Baralle; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HML; ISCU; Splicing; SRSF3; PTBP1; RBM39; MBNL1; medicinsk genetik; Medical Genetics;

    Sammanfattning : Patients suffering from hereditary myopathy with lactic acidosis (HML) can be found in the northern Swedish counties of Ångermanland and Västerbotten. HML is a rare autosomal recessive disease where patients display a low tolerance to exercise at an early age. LÄS MER

  3. 12. Adenovirus vector systems permitting regulated protein expression and their use for in vivo splicing studies

    Författare :Magnus Molin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Adenovirus; vector; inducible; gene expression; ASF SF2; splicing; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : We have constructed two adenovirus-based gene expression vector systems permitting regulated protein expression. They are based on the tetracycline-regulated Tet-ON- and the progesterone antagonist RU 486-regulated gene expression systems, which were rescued into E1-deficient adenovirus vectors. LÄS MER

  4. 13. Regulation of pre-mRNA editing and splicing : the role of the tumour suppressor gene product WT1 in pre-mRNA splicing : coordination of base modification editing by ADAR and pre-mRNA splicing

    Författare :Eva Bratt; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA;

    Sammanfattning : .... LÄS MER

  5. 14. Splicing of adenovirus-2 E1A pre-messenger RNA : sequence requirement and the biological consequences of alternative RNA splicing

    Författare :Per Johan Ulfendahl; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  7. 15. Viral Control of SR Protein Activity

    Författare :Camilla Estmer Nilsson; Neus Visa; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; adenovirus; ASF SF2; dephosphorylation; E4-ORF4; L1; MLTU; PP2A; splicing; SR proteins; vaccinia virus; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : Viruses modulate biosynthetic machineries of the host cell for a rapid and efficient virus replication. One important way of modulating protein activity in eukaryotic cells is by reversible phosphorylation. In this thesis we have studied adenovirus and vaccinia virus, two DNA viruses with different replication stategies. LÄS MER