Sökning: "splicing"

Visar resultat 21 - 25 av 236 avhandlingar innehållade ordet splicing.

  1. 21. The Role of Polyadenylation in Human Papillomavirus Type 16 Late Gene Expression

    Författare :Daniel Öberg; Stefan Schwartz; Sheila Graham; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; HPV-16; polyadenylation; mRNA stability; codon usage; hnRNP H; DSE; splicing; negative element; RNA processing; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Sammanfattning : High-risk type human papillomaviruses (HPVs) are associated with cancer. HPVs are strictly epitheliotropic and infect basal cell layers, establishing a life cycle strongly linked to the differentiation stage of the infected cells. The viral capsid late genes, L2 and L1, are only expressed in terminally differentiated epithelium. LÄS MER

  2. 22. Large eddy simulation of combustion using linear-eddy subgrid modeling

    Författare :Salman Arshad; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; LES-LEM; splicing; turbulent combustion; super-grid LES-LEM; CFD; linear eddy model; reaction-rate closure; large eddy simulation;

    Sammanfattning : As emissions regulations are getting stricter and efficiency requirements of internal combustion engines (ICE) are increasing, different concepts to improve combustion are being investigated. For example lean stratified premixed combustion, homogeneous charge compression ignition (HCCI), use of more exhaust gas recirculation (EGR) to reduce NOx etc. LÄS MER

  3. 23. The SWI/SNF complex : Roles in transcription and pre-mRNA processing

    Författare :Johan Waldholm; Neus Visa; Ann-Kristin Östlund; Silvia Barabino; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Splicing; Gene regulation; SWI SNF; polyadenylation; Molecular Biology; molekylärbiologi;

    Sammanfattning : The regulation of gene expression is fundamental to the development of complex organisms and an important driving force in this process. When and where the genes are expressed decide the fate of a cell and its physiological context in the organism. LÄS MER

  4. 24. The Multifunctional Nature of the Adenovirus L4-22K Protein

    Författare :Susan Lan; Göran Akusjärvi; Per Elias; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; L4-22K; MLP; RNA; transcription; splicing; adenovirus;

    Sammanfattning : The adenovirus major late transcription unit (MLTU) encodes for most of the mRNAs that are translated into the structural proteins of the virus capsid. Transcription from the MLTU is directed by the major late promoter (MLP), which is highly activated during the late phase of infection. LÄS MER

  5. 25. Biomolecular Analysis by Dual-Tag Microarrays and Single Molecule Amplification

    Författare :Olle Ericsson; Ulf Landegren; Mats Nilsson; Edwin Southern; Uppsala universitet; []
    Nyckelord :Molecular medicine; Microarray; proximity ligation; Padlock probe; Rolling circle amplification; Splicing; single molecule; Molekylärmedicin;

    Sammanfattning : Padlock probes and proximity ligation are two powerful molecular tools for detection of nucleic acids and proteins, respectively. Both methods result in the formation of DNA reporter molecules upon recognition of specific target molecules. LÄS MER