Sökning: "splicing"

Visar resultat 1 - 5 av 197 avhandlingar innehållade ordet splicing.

  1. 1. Regulation of adenovirus alternative pre-mRNA splicing Functional characterization of exonic and intronic splicing enhancer elements

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Bai-Gong Yue; Uppsala universitet.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; adenovirus; pre-mRNA splicing; splicing enhancer; MLTU; L1; SR protein; ASF SF2; E. coli; phosphorylation; dephosphorylation; Biokemi; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; mikrobiologi; Microbiology;

    Sammanfattning : Pre-mRNA splicing and alternative pre-mRNA splicing are key regulatory steps controlling geneexpression in higher eukaryotes. The work in this thesis was focused on a characterization of thesignificance of exonic and intronic splicing enhancer elements for pre-mRNA splicing. LÄS MER

  2. 2. Regulation of Human Papillomavirus Type 16 Late L1 mRNA Splicing

    Detta är en avhandling från Division of Medical Microbiology, Lund University

    Författare :Xiaoze Li; Lunds universitet.; Lund University.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HPV-16; cervical cancer; RNA processing; alternative splicing; splicing enhancer; splicing silencer; viral persistance; SR proteins; hnRNP proteins;

    Sammanfattning : Popular Abstract in English Each year an estimated 530 000 new cases of cervical cancer are diagnosed and more than 275 000 women die from cervical cancer worldwide (2). Cervical cancer is caused by sexually-acquired infections with a subset of human papillomavirus (HPV) (359, 360). LÄS MER

  3. 3. The Adenovirus L4-33K Protein A Key Regulator of Virus-specific Alternative Splicing

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Heidi Törmänen Persson; Uppsala universitet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; L4-33K; adenovirus; splicing; phosphorylation; localization; replication centers; L4-22K; MLTU; DNA-PK; DNA-dependent protein kinase; PKA; cAMP-dependent protein kinase; transcription sites; SR protein; Medical Virology; Medicinsk virologi;

    Sammanfattning : Adenoviruses have been extensively studied in the field of gene regulation, since their genes are subjected to a tightly controlled temporal expression during the virus lifetime. The early-to-late shift in adenoviral gene expression distinguishes two completely different programs in gene expression. LÄS MER

  4. 4. The Modular Domain Structure of ASF/SF2: Significance for its Function as a Regulator of RNA Splicing

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Vita Dauksaite; Uppsala universitet.; [2003]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; pre-mRNA splicing; alternative splicing; splicing regulation; SR proteins; ASF SF2; modular domains; adenovirus; MLTU L1; E1A; MS2; Molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi;

    Sammanfattning : ASF/SF2 is an essential splicing factor, required for constitutive splicing, and functioning as a regulator of alternative splicing. ASF/SF2 is modular in structure and contains two amino-terminal RNA binding domains (RBD1 and RBD2), and a carboxy-terminal RS domain. LÄS MER

  5. 5. Viral Strategies to Regulate Transcription and Pre-mRNA Splicing

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Shaoan Fan; Uppsala universitet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Adenovirus E1B-55kDa; E4-ORF4; E4-ORF6 proteins; L1 mRNA; Polyoma virus small T antigen; regulation; transcription; splicing; PP2A; Biokemi; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : A typical DNA virus encodes for a few key regulatory proteins that modify the host cell biosynthetic machinery to achieve a selective viral gene statement. One such example is illustrated by the adenovirus E4-ORF4 protein, which form an enzymatically active complex with the serine and threonine-specific protein phosphatase 2A (PP2A). LÄS MER