Sökning: "vaccinia virus"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden vaccinia virus.

  1. 1. Envelopment of retrovirus and vaccinia virus

    Författare :Kristina Wallengren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Retrovirus; Vaccinia virus; Envelopment; Host proteins; Gag-particles; IMV A17L.;

    Sammanfattning : This thesis describes envelopment of retrovirus and vaccinia virus. Retrovirus envelopment, i.e. budding, occurs from the plasma membrane (PM) of infected cells in an environment that is abundant with cellular proteins. LÄS MER

  3. 2. Viral Control of SR Protein Activity

    Författare :Camilla Estmer Nilsson; Neus Visa; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; adenovirus; ASF SF2; dephosphorylation; E4-ORF4; L1; MLTU; PP2A; splicing; SR proteins; vaccinia virus; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Sammanfattning : Viruses modulate biosynthetic machineries of the host cell for a rapid and efficient virus replication. One important way of modulating protein activity in eukaryotic cells is by reversible phosphorylation. In this thesis we have studied adenovirus and vaccinia virus, two DNA viruses with different replication stategies. LÄS MER

  4. 3. Virus Host Interactions in SARS Coronavirus Infection

    Författare :Vithiagaran Gunalan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The global outbreak of Severe Acute Respiratory Syndrome which began in 2002 and ended in 2003 resulted in over 8000 cases in 29 countries, causing an atypical pneumonia which resulted in a case fatality rate of ~10%. The etiological agent of this disease was found to be a novel coronavirus dubbed SARS Coronavirus (SARS-CoV). LÄS MER

  5. 4. Control of Epstein-Barr virus infection by cytotoxic T lymphocytes

    Författare :Pedro-Otavio de Campos-Lima; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Epstein-Barr virus; Cytotoxic T lymphocytes; T cell receptor; CTLescape mutants;

    Sammanfattning : Cytotoxic T lymphocytes (CTL) play a critical role in response to Epstein-Barr virus (EBV), a widespread human herpes virus that persists in healthy carriers as a latent infection of B cells and is implicated in the pathogenesis of lymphoid and epithelial cell malignancies. Six virus encoded nuclear antigens, EBNA1-6, and three membrane proteins, LMP1, -2A and -2B, are regularly detected in EBV transformed lymphoblastoid cell lines (LCLs). LÄS MER

  7. 5. Mapping the Golgi retention signal in the G1 membrane glycoprotein of Uukuniemi virus, a member of the Bunyaviridae family

    Författare :Agneta M Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Golgi complex; retention signal; protein transport; virus membrane glycoproteins; virus budding; Uukuniemi virus; Phlebovirus; Bunyaviridae;

    Sammanfattning : Newly synthesized secretory and integral membrane proteins destined for the plasma membrane are transported along the exocytic pathway from the endoplasmic reticulum (ER) via the Golgi complex (GC) to the cell surface. Some of the transported proteins contain information, which target them to their correct intracellular locations. LÄS MER