Sökning: "signal transduction molecules"

Visar resultat 16 - 20 av 68 avhandlingar innehållade orden signal transduction molecules.

  1. 16. Profilin in cell motility and signal transduction studies using site-specific mutagenesis

    Författare :Camilla Björkegren Sjögren; Tommy Andersson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell biology; Cellbiologi; Zoological Cell Biology; zoologisk cellbiologi;

    Sammanfattning : When a cell is stimulated by signalling molecules such as growth factors, one immediate response is an increased motile activity of the cell. Membrane lamella and spikes appear at the cell surface and perform undulating movements. LÄS MER

  3. 17. Signal transduction via ion fluxes : a cell imaging study with emphasis on calcium oscillations

    Författare :Per Uhlén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Calcium; Ca2 signalling; Ca2 oscillation; InsP3; InsP3 receptor; Na; K-ATPase; ouabain; physical interaction; FRET; spectral analysis; confocal microscopy;

    Sammanfattning : Signal transduction via ion fluxes is of vital importance for all mammalian cells. Cells can exploit ion regulatory mechanisms to generate and transmit intracellular signals. Improvements in digital microscopic imaging technology have made it possible to explore micro-environments and complex intracellular machineries. LÄS MER

  4. 18. Modelling T helper cell activation and development

    Författare :Andreas Jansson; Högskolan i Skövde; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; T cells; mathematical models; differentiation; computer simulation; mathematical models; cellular signal transduction; Bioinformatics; Bioinformatik; Natural sciences; Naturvetenskap; Technology; Teknik;

    Sammanfattning : T helper (Th) cell activation and development is one of the most critical events in regulating the adaptive immune response. Understanding its regulation could be of great therapeutical value as many severe diseases are associated with failure in controlling T cell activation and development. LÄS MER

  5. 19. Frizzled as a G protein-coupled receptor : the role of disheveled and G proteins for signal specification

    Författare :Michaela Kilander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cell communication governed and coordinated by the WNT family of lipoglycoproteins comprises essential physiological processes active throughout the life-span of metazoan organisms. In humans, severe diseases and congenital birth defects have been directly linked to disturbances in WNT signaling. LÄS MER

  7. 20. Molecular dissection of B-lymphocyte signalling using expression profiling

    Författare :Jessica M Lindvall; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Btk; B-lymphocyte; gene expression profiling; signal transduction;

    Sammanfattning : Gene expression profiling and bioinformatics have emerged into playing a large and diverse role in many aspects of both the clinical and molecular research. These two approaches have in this thesis work been used in combination in order to shed light to the role of Bruton's tyrosine kinase (Btk) in B-lymphocyte development and signal transduction. LÄS MER