Sökning: "K-ATPase"
Visar resultat 1 - 5 av 73 avhandlingar innehållade ordet K-ATPase.
1. The Biophysics of Na+,K+-ATPase in neuronal health and disease
Sammanfattning : Na+,K+-ATPase is one of the most important proteins in the mammalian cell. It creates sodium and potassium gradients which are fundamental for the membrane potential and sodium-dependent secondary active transport. LÄS MER
2. Novel aspects of Na+,K+-ATPase
Sammanfattning : Na,K-ATPase, an integral membrane protein expressed in each eukaryotic cell, serves as the major determinant of intracellular ion composition. In the current study we investigated novel aspects of Na,K-ATPase function and regulation. It is well established that Na,K-ATPase activity is regulated by reversible phosphorylation. LÄS MER
3. Na,K-ATPase as signaling transducer
Sammanfattning : It is now generally agreed that Na,K-ATPase (NKA), in addition to its role in the maintenance of Na+ and K+ gradients across the cell membrane, is a signal transducer. Our group has identified a novel signaling pathway where NKA interact with IP3R to form a signaling microdomain. LÄS MER
4. Transport of sodium and protons in the human placenta. Mechanisms in normal pregnancy and alterations in intrauterine growth restriction
Sammanfattning : The syncytiotrophoblast cell of the human placenta represents the interface between maternal and fetal blood supplies. This polarized epithelium consists of a maternal facing microvillous membrane (MVM) opposing a fetal facing basal membrane (BM). This unique syncytial cell is responsible for transfer of all nutrients to the developing fetus. LÄS MER
5. Role of Na+,K+-ATPase in cell adhesion and cell volume regulation : mutagenesis of Na+,K+-ATPase and transfection in embryonic kidney cell line
Sammanfattning : The regulation of Na+,K+-ATPase activity by hormones and neurotransmittors via intracellular signaling molecules such as kinases and phosphatases, occurs in several physiological situations in vivo. Alterations of Na+,K+ATPase activity as a result of pathophysiological mechanisms have been shown to be involved in the final outcome of the pathological process. LÄS MER