Sökning: "Per Uhlén"
Hittade 4 avhandlingar innehållade orden Per Uhlén.
1. Signal transduction via ion fluxes : a cell imaging study with emphasis on calcium oscillations
Sammanfattning : Signal transduction via ion fluxes is of vital importance for all mammalian cells. Cells can exploit ion regulatory mechanisms to generate and transmit intracellular signals. Improvements in digital microscopic imaging technology have made it possible to explore micro-environments and complex intracellular machineries. LÄS MER
2. Host-parasite interactions in the dissemination of Toxoplasma gondii
Sammanfattning : Toxoplasma gondii is an obligate intracellular parasite that infects virtually all warm-blooded organisms. Systemic dissemination of T. gondii in the organism can cause life-threatening infection that manifests as Toxoplasma encephalitis in immune-compromised patients. LÄS MER
3. The Frequency of the Frequency : On Hydropower and Grid Frequency Control
Sammanfattning : Variations in the electricity consumption and production connected to the power system have to be balanced by active control. Hydropower is the most important balancing resource in the Nordic system, and will become even more important as the share of variable renewable energy sources increases. LÄS MER
4. Rational and Combinatorial Engineering of Affinity Proteins Towards Therapeutical Applications
Sammanfattning : Protein engineering has had an immense impact on the development of biological drugs, including replacement therapies with engineered versions of insulin or factor VIII to treat diabetes or bleeding disorders, and monoclonal antibodies to treat cancer and various other malignancies. Now, with the next generation of treatment modalities coming up, including monoclonal reagents based on alternative scaffolds, gene and cell therapies, the importance of protein engineering to tailor-make these treatments is likely to increase further. LÄS MER