Sökning: "Ca2 signalling"
Visar resultat 1 - 5 av 74 avhandlingar innehållade orden Ca2 signalling.
1. Ca2+ signalling in the pancreatic ß-cell : studies of the mechanisms for intracellular release and sequestration of Ca2+
Sammanfattning : .... LÄS MER
2. α-Cell signalling in glucose-regulated glucagon secretion
Sammanfattning : Glucagon is a blood glucose-elevating hormone released from α-cells in the islets of Langerhans during hypoglycaemia. Glucagon is critical for glucose homeostasis and inappropriate regulation of its secretion underlies both impaired counter-regulation of hypoglycaemia and chronic hyperglycaemia in diabetes patients. LÄS MER
3. Injury-Induced Signalling in Arterial Smooth Muscle Cells
Sammanfattning : The vascular wall is an active, elastic and integrated organ made up of cellular and extracellular matrix (ECM) components. It is not a static organ; the components dynamically change and reorganize in response to physiological and pathological stimuli. Vascular injury induces a complex healing process, analogous to generalised wound healing. LÄS MER
4. Effects of Ca2+, microRNAs, and rosuvastatin on insulin-secreting beta cell function
Sammanfattning : Type 2 diabetes (T2D) is a condition of high blood glucose levels due to insulin resistance and defective insulin secretion. Impaired insulin secretion plays a major role in the pathophysiology of T2D, it is mainly attributed to beta cell function i.e. failure to secrete insulin or reduced beta cell mass. LÄS MER
5. OX1 Orexin Receptor Signalling to Phospholipases
Sammanfattning : The neuropeptides orexin-A and orexin-B were discovered in 1998 and were first described as regulators of feeding behaviour. Later research has shown that they have an important role in the regulation of sleep. Two G protein-coupled receptors, OX1 and OX2 orexin receptors, mediate the cellular responses to orexins. LÄS MER