Sökning: "cellular signal transduction"
Visar resultat 1 - 5 av 125 avhandlingar innehållade orden cellular signal transduction.
1. TRAF6 stimulates TGFβ-induced oncogenic signal transduction in cancer cells
Sammanfattning : Prostate cancer is one of the leading causes of cancer-related deaths in men worldwide, with 10,000 new cases/year diagnosed in Sweden. In this context, there is an urgent need to identify new biomarkers to detect prostate cancer at an initial stage for earlier treatment intervention. LÄS MER
2. ß2 integrin-induced signal transduction events in human neutrophils
Sammanfattning : Inflammation is a localized protective response in vascularized tissues and can be induced by microbial infection or cell and tissue injury. Polymorphonuclear neutrophils (PMN) are the most common white blood cells and are recognized as major cellular mediators of acute inflammation. LÄS MER
3. The Tyrosine Kinase GTK : Signal Transduction and Biological Function
Sammanfattning : Protein tyrosine kinases play an important role in the regulation of various cellular processes such asgrowth, differentiation and survival. GTK, a novel SRC-like cytoplasmic tyrosine kinase, was recently cloned from a mouse insulinoma cell line and the present work was conducted in order to find a biological function of GTK in insulin producing and neuronal cells. LÄS MER
4. Fibroblast growth factor-induced signal transduction
Sammanfattning : Fibroblast growth factors (FGFs) evoke cellular responses by binding to FGF receptors (FGFRs). FGFRs are cell surface expressed membrane-spanning receptors with intrinsic stimulatable tyrosine kinase activity. This thesis describes the cell proliferation or differentiation. LÄS MER
5. Robustness analysis of eukaryotic signal transduction with emphasis on the HOG pathway in Saccharomyces cerevisiae
Sammanfattning : Fundamental to life, in particular for unicellular microorganisms that generally are subjected to rapidly changing environmental parameters, is the need to monitor and integrate environmental stimuli with the internal cell status. The sensing of stimuli are typically initiated at the plasma membrane and then transmitted by means of intracellular signalling networks to elicit proper cellular responses. LÄS MER