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Visar resultat 1 - 5 av 448 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Prostate Cancer Screening - Aspects of Overdiagnosis

   Författare :Rebecka Arnsrud Godtman; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; active surveillance; age; cause of death; opportunistic; organized; overdiagnosis; prostate cancer; prostate-specific antigen; risk factors; screening; screening interval;

   Sammanfattning : The overall aim of this thesis is to explore aspects of overdiagnosis, i.e. the diagnosis of a tumor that in the absence of screening would never have been diagnosed, in prostate cancer (PC) screening. LÄS MER

3. 2. Quiescent cancer cells : Three-dimensional cell models for evaluation of new therapeutics

   Författare :Frida Ek; Mårten Fryknäs; Malin Jarvius; Rolf Larsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; cancer cell quiescence; dormancy; three-dimensional; multicellular tumor spheroids; model development; cancer pharmacology; mitochondria; OXPHOS; colorectal carcinoma; hepatocellular carcinoma; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Inadequate metabolic conditions in solid tumors lead to the formation of quiescent cancer cells that are suspended in a transient cell cycle arrest. When conditions change, quiescent cancer cells can re-enter the cell cycle and cause recurrence. LÄS MER

4. 3. Someone has to tell them : exploring hereditary cancer risk disclosure in Sweden

   Författare :Carolina Hawranek; Anna Rosén; Senada Hajdarevic; Beatrice S. Melin; Barbro Numan Hellquist; Maria Katapodi; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; hereditary cancer; prevention; family disclosure; family communication; cancer worry; risk information; at-risk relatives; cascade testing; genetic counselling; public opinion; Oncology; onkologi; Genetics; genetik;

   Sammanfattning : Summary in EnglishBackground: An awareness of hereditary susceptibility for breast, ovarian and colorectal cancer in high-risk families enables targeted cancer prevention. A discovered hereditary risk in one family member (proband) may thus be important for several members of that family. LÄS MER

5. 4. Circulating markers of risk and etiology in colorectal cancer

   Författare :Justin Harbs; Sophia Harlid; Bethany van Guelpen; Xijia Liu; Henrik Grönberg; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; CRC; sex hormones; colon cancer; DNA methylation; proteomics; risk; etiology; Cancer Epidemiology; cancerepidemiologi;

   Sammanfattning : Background: Colorectal cancer is the third most commonly diagnosed cancer in men and women. Worldwide around 2 million individuals are diagnosed each year – a number expected to increase as colorectal cancer risk factors become more prevalent. LÄS MER

7. 5. Characteristics of screen-failures in prostate cancer screening

   Författare :Anna Grenabo Bergdahl; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; screening; prostate cancer; screening failures; antigen; age; interval cancer; multiparametric magnetic resonance imaging; non-attendees; prostate cancer screening;

   Sammanfattning : ABSTRACT Although prostate-specific antigen (PSA)-based screening has been shown to reduce prostate cancer (PC)-specific mortality with large variations in mortality reduction with different screening algorithms, the optimal screening strategy has not yet been established. This thesis aims at exploring aspects of underdiagnosis in PC screening, focusing on the impact of screening failures on screening effectiveness. LÄS MER