Sökning: "risk minimization"

Visar resultat 6 - 10 av 23 avhandlingar innehållade orden risk minimization.

  1. 6. Hazards of Drug Therapy : On the Management of Adverse Drug Reactions: From Signal Detection and Evaluation to Risk Minimization

    Författare :Karin Hedenmalm; Marja-Liisa Dahl; Gunnar Alvan; Ellen Vinge; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; adverse drug reactions; spontaneous reporting systems; drug regulation; pharmacovigilance; incidence; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Sammanfattning : Spontaneous reporting systems (SRSs) for adverse drug reactions (ADRs) have been developed as a result of the thalidomide disaster, whereby thousands of children world-wide were born with birth defects. The Swedish Adverse Drug Reactions Advisory Committee was established in 1965. LÄS MER

  2. 7. Pre-crash Motion Planning for Autonomous Vehicles in Unavoidable Collision Scenarios

    Författare :Masoumeh Parseh; Martin Törngren; Fredrik Asplund; Daniel Watzenig; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Autonomous vehicles; motion planning; severity minimization; data-driven; safety; collision mitigation; vehicle dynamics; vehicle control; collision reconfiguration; post-impact; collision model; Autonoma fordon; rörelseplanering; skademinimering; datadriven; personsäkerhet; säkerhet; mildring av effekterna av kollisioner; fordonsdynamik; fordonskontroll; omkonfigurering av kollisioner; efter kollisioner; kollisionsmodell; Machine Design; Maskinkonstruktion;

    Sammanfattning : Full deployment of Autonomous Vehicles (AVs) on public roads is challenging for organizations in the automotive domain in terms of developing safety standards and methods while taking legacy assumptions related to having a human driver and increased complexity and complexity handling into account. Specifically, the safety of AVs in the presence of other road users must be guaranteed as far as possible for different traffic scenarios. LÄS MER

  3. 8. Urban women applying for induced abortion. Studies of epidemiology, attitudes and emotional reactions

    Författare :Hanna Söderberg; gynekologisk och prenatal ultraljudsdiagnostik Obstetrisk; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrik; reproduction; sexuality; andrology; Obstetrics; gynaecology; Induced abortion; risk areas; continued pregnancy; socio-demographic differences; reasons for abortion; interview study; selection bias; emotional distress; repeat abortion; ethnic problems; use of an compliance with contraceptives; gynekologi; andrologi; reproduktion; sexualitet;

    Sammanfattning : In Sweden between 32-38,000 women annually elect to terminate pregnancy by means of induced abortion, though their reasons are still not well understood. The purpose of these studies, carried out at the Department of Obstetrics and gynecology and of Community Medicine at University Hospital, Malmö, was to elucidate the incidence of induced abortion in an urban population, with special emphasis on epidemiological and socio-demographic factors, the women's attitude to abortion, and the incidence and severity of post-abortion emotional reactions. LÄS MER

  4. 9. Genetics of Osteoporosis - Studies on bone size, structure and strength in the rat

    Författare :Sofia Lagerholm; Ortopedi - klinisk och molekylär osteoporosforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Osteoporosis is characterized by decreased bone mineral density (BMD) leading to reduced bone strength and increased fracture risk. Several heritable components affect a bone’s ability to resist fracture, including size, structure and strength; therefore identification of the genes underlying several bone characteristics will help elucidate the pathogenesis of fracture risk. LÄS MER

  5. 10. Using Pharmacokinetic and Pharmacodynamic Principles to Evaluate Individualisation of Antibiotic Dosing – Emphasis on Cefuroxime

    Författare :Anders Viberg; Marie Sandström; Otto Cars; Mats Karlsson; Hartmut Derendorf; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacokinetics Pharmacotherapy; Cefuroxime; pharmacokinetics; pharmacodynamics; dosing individualisation; NONMEM; Farmakokinetik Farmakoterapi; PHARMACY; FARMACI;

    Sammanfattning : Cefuroxime is a renally eliminated antibiotic used against a variety of different bacterial infections. The pharmacokinetics (PK) for cefuroxime was studied in 97 hospitalized patients using population analysis. To be able to measure cefuroxime in human serum a new sensitive analytical method was developed using mass spectrometry detection. LÄS MER