Sökning: "recombinant tissue-type plasminogen activator"

Hittade 4 avhandlingar innehållade orden recombinant tissue-type plasminogen activator.

  1. 1. Experimental studies on thrombosis and thrombolysis : With special reference to importance of lys-plasminogen, active site thrombin inhibitors and stable fish oil

    Författare :Liying Chen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Thrombolysis; thrombosis; recombinant tissue-type plasminogen activator; lys- and glu-plasminogen; aspirin; thrombin inhibitors; platelets; superoxide dismutase; stable fish oil; Kirurgi; Surgery; Kirurgi; rättsmedicin; Forensic Medicine;

    Sammanfattning : Dissolution and prevention of thrombus in the atherosclerotic coronary artery have become an important part of treatment therapy of acute myocardial infarction. However, the currently most effective thrombolytic agent, recombinant tissue-type plasminogen activator (rt-PA), only elicits 80% recanalization of thrombotically occluded coronary arteries and early occlusion occurs in about 40% of successfullyrecanalized vessels. LÄS MER

  3. 2. The significance of urokinase-type plasminogen activator (u-PA) in tumour growth and Linomide-induced upregulation of u-PA's endogenous inhibitor PAI-2

    Författare :Anita Billström; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reproduction; andrology; gynaecology; Obstetrics; roquinimex; Linomide; cancer; prostate cancer; PAI-2; plasmin; Plasminogen activators; u-PA; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : The progressive process of tumour invasion and generation of metastases is the primary cause of death for most patients with cancer. Some of the regulatory components of this progressive process are adhesion, migration, and proteolysis. LÄS MER

  4. 3. Endogenous t-PA release and pharmacological thrombolysis - Experimental animal studies of the coronary circulation

    Författare :Jan-Arne Björkman; Göteborgs universitet; []
    Nyckelord :Klinisk fysiologi;

    Sammanfattning : Abstract The physiologically most important activator of intravascular fibrinolysis is tissue-type plasminogen activator (t-PA) released from endothelial cells. In man, sympathomimetic drugs increase the systemic concentration of t-PA. LÄS MER

  5. 4. Unstable coronary artery disease : non-invasive indicators of severity of coronary lesions and the effects of thrombolysis

    Författare :Jan-Erik Karlsson; Rolf Nordlander; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Non-invasive indicators of severity of coronary lesions and the effects of thrombolysis were evaluated in 205 men, 38 to 70 years of age with unstable coronary aticty disease (CAD)- i.e. unstable angina or non-Q wave myocardial infarction - admitted to the coronary care units in nine hospitals. LÄS MER