Sökning: "protein family"

Visar resultat 21 - 25 av 1132 avhandlingar innehållade orden protein family.

  1. 21. Bax and oxidized phospholipids - a deadly complex : Apoptotic protein-lipid assemblies studied by MAS NMR spectroscopy

    Författare :Artur Dingeldein; Gerhard Gröbner; Mikael Elofsson; Tobias Sparrman; Daniel Topgaard; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; mitochondrial membranes; apoptosis; membrane dynamics and organization; Bcl-2 family proteins; Bax protein; biokemi; Biochemistry;

    Sammanfattning : Mitochondria are renowned for their vital role as cellular powerhouses because they provide ATP via cellular respiration. Additionally, these organelles also play an important role in other physiological processes, such as apoptosis. LÄS MER

  3. 22. The effect of sequence truncation and amino-acid substitutions on the biophysical properties of protein S and calbindin D9k

    Författare :Karin Julenius; Biofysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; surface plasmon resonance; fluorescence spectroscopy; circular dichroism spectroscopy; NMR spectroscopy; hydrophobic effect; protein stability; dimerization; cooperativity; calcium binding; EGF-module; EF-hand; calbindin D9k; protein S; synthet; Physical chemistry; Fysikalisk kemi;

    Sammanfattning : Protein S is a modular protein and a cofactor in the protein C anticoagulant system. It consists of a Gla-module, a thrombin-sensitive loop, four EGF-modules and a SHBG-like module. LÄS MER

  4. 23. The cholecystokinin receptor family : molecular cloning and pharmacological characterization

    Författare :Isabelle Nilsson; Dan Larhammar; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Cholecystokinin (CCK) and gastrin are hormones/neurotransmittors of the gastrointestinal tract and central nervous system. The receptors for gastrin and CCK are members of the G protein-coupled receptor family. The aim of this study was to clone and pharmacologically characterize vertebrate and invertebrate CCK receptors and splice variants. LÄS MER

  5. 24. Prediction, Design and Determination of Protein Structures

    Författare :Sebastian Rämisch; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein design; Rosetta; Fold-and-Dock; leucine rich repeat proteins; coiled-coils; molecular replacement; ab initio phasing; temperature stability; fluorescent proteins;

    Sammanfattning : The three-dimensional structure of protein is encoded in its amino acid sequence. Modern structure prediction algorithms make it possible to predict the structure of small proteins using sequence information alone. LÄS MER

  7. 25. Mutational effects on protein structure and function

    Författare :Jonas Carlsson; Persson Bengt; Uwe Sauer; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mutation; prediction; phenotypes; homology model; virtual screening; molecular dynamics; amyloid; cancer; membrane protein; Bioinformatics; Bioinformatik;

    Sammanfattning : In this thesis several important proteins are investigated from a structural perspective. Some of the proteins are disease related while other have important but not completely characterised functions. LÄS MER