Sökning: "membrane dynamics and organization"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden membrane dynamics and organization.

1. 1. Cell signaling by Rho and Miro GTPases : Studies of Rho GTPases in Cytoskeletal Reorganizations and of Miro GTPases in Mitochondrial Dynamics

   Författare :Åsa Fransson; Pontus Aspenström; Harry Mellor; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ras superfamily; Rho GTPases; cytoskeleton; Miro GTPases; mitochondrial dynamics; Cell and molecular biology; Cell- och molekylärbiologi;

   Sammanfattning : The Ras superfamily of GTPases embraces six major branches of proteins: the Ras, Rab, Ran, Arf, Rho and Miro subfamilies. The majority of GTPases function as binary switches that cycle between active GTP-bound and inactive GDP-bound states. This thesis will focus primarily on the biological functions of the Rho and Miro proteins. LÄS MER

3. 2. Lipid Nanotube Networks: Shape Transitions and Insights into the Dynamics of Self-Organization

   Författare :Tatsiana Lobovkina; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; circular nanotube; shape transition; enzymatic reaction; nanotube knot; self-organization; liposome; lipid nanotube; lipid vesicle; nanotube-vesicle network;

   Sammanfattning : Nanotube-vesicle networks (NVNs) are simplified models of cell membrane tubular systems which are dynamic transportation routs for molecular cargoes in biological cells. The presented work describes dynamic properties of NVNs such as self-organization, shape and topology transformations; moreover, specific geometric properties of the networks are used for controlling enzymatic reactions. LÄS MER

4. 3. Microbial Community Assembly during Aerobic Granulation

   Författare :Raquel Liebana; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; aerobic granular sludge; granulation; washout dynamics; membrane bioreactors; sequencing batch reactors; fluorescence in-situ hybridization; microbial community dynamics; reproducibility;

   Sammanfattning : Environmental deterioration together with the increasingly restrictive legislation of water quality standards have led to a demand for compact, efficient and less energy consuming technologies for wastewater treatment. Aerobic granular membrane bioreactors (AGMBRs) combine the advantages of aerobic granular sludge and membrane filtration. LÄS MER

5. 4. RICH-1, a Multifunctional RhoGAP Domain-containing Protein, Involved in Regulation of the Actin Filament System and Membrane-trafficking

   Författare :Ninna Richnau; Pontus Aspenström; Carl-Henrik Heldin; Bengt Hallberg; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Rho GTPase; RhoGAP; actin; BAR domain; membrane-trafficking; formin homology proteins; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

   Sammanfattning : The Rho GTPases, which are related to the Ras family of proto-oncogenes, have been found to have important roles in regulating the morphogenic and migratory properties of eukaryotic cells. In addition, these proteins have been shown to regulate aspects of cell signaling, cell growth, cell division and cell survival. LÄS MER

7. 5. Plasma membrane order; the role of cholesterol and links to actin filaments

   Författare :Jelena Dinic; Ingela Parmryd; Gerrit van Meer; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Membrane Organization; Lipid rafts; Actin; Laurdan; di-4-ANEPPDHQ; Cholesterol; T cell signaling; Colocalization; Generalized Polarization; Cell Biology; cellbiologi;

   Sammanfattning : The connection between T cell activation, plasma membrane order and actin filament dynamics was the main focus of this study. Laurdan and di-4-ANEPPDHQ, membrane order sensing probes, were shown to report only on lipid packing rather than being influenced by the presence of membrane-inserted peptides justifying their use in membrane order studies. LÄS MER