Sökning: "platelet aggregation"

Visar resultat 6 - 10 av 82 avhandlingar innehållade orden platelet aggregation.

  1. 6. Platelet Inhibition and Bleeding Complications in Cardiac Surgery Patients - Clinical and experimental studies

    Författare :Emma C. Hansson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute coronary syndrome; Bleeding complications; Cardiac surgery; Platelet aggregation inhibitors; Platelet transfusion;

    Sammanfattning : BACKGROUND AND OBJECTIVE Dual antiplatelet therapy (DAPT) with acetylsalicylic acid and a P2Y12 inhibitor (clopidogrel, ticagrelor, or prasugrel) reduces thrombotic events in patients with acute coronary syndrome (ACS), but it is also associated with an increased risk of bleeding complications. The aim of this project was to investigate the prevalence and effects of platelet inhibition in the context of cardiac surgery, the bleeding problems that may occur, and treatment of bleeding complications. LÄS MER

  3. 7. Immobilization as a risk factor for arterial and venous thrombosis

    Författare :Karin Arinell; Ole Frøbert; Kjeld Christensen; Tal Hörer; Joakim Alfredsson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Venous thrombosis; arterial thrombosis; atherosclerosis; cystatin C; cholesterol; platelet activation; platelet aggregation; immobilization;

    Sammanfattning : Aim: Immobilization and a sedentary lifestyle are correlated with an elevated risk of both arterial and venous thrombosis. The goal of this research was to investigate whether markers associated with cardiovascular disease risk are altered during long term immobilization in a human model and in the brown bear, which survives annual cycles of long-term immobilization. LÄS MER

  4. 8. Streptococci and Platelets - A Study of Host-Pathogen Interaction Dynamics

    Författare :Lisbeth Svensson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; host-pathogen interactions; bacterial entrapment; disaggregation; aggregation; platelet activation; Streptococci;

    Sammanfattning : Invasive infections remains one of the leading causes of death due to infections over the world, and efficient treatment remains elusive. One of the major causes of sepsis and other invasive infections is pathogenic streptococci that cause a wide range of clinical manifestations in humans. LÄS MER

  5. 9. The Role of Chlamydia pneumoniae-induced Platelet Activation in Cardiovascular Disease : In vitro and In vivo studies

    Författare :Hanna Kälvegren; Torbjörn Bengtsson; Arina Richter; Erik Kihlström; Kenneth Persson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chlamydia pneumoniae; Platelet; atherosclerosis; Infection; LDL-oxidation; Percutaneous coronary intervention; Cardiovascular disease; Serotonin; Reactive oxygen species production; Pharmacology; Farmakologi;

    Sammanfattning : The common risk factors for atherosclerosis, such as obesity, high cholesterol levels, sedentary lifestyle, diabetes and high alcohol intake, only explain approximately 50% of cardiovascular disease events. It is thereby important to identify new mechanisms that can stimulate the process of atherosclerosis. LÄS MER

  7. 10. Fibrinogen, platelet and factor XIII supplementation in cardiac surgery: In vitro and in vivo studies

    Författare :Caroline Andersson Shams Hakimi; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fibrinogen; platelets; factor XIII; platelet aggregation; clot formation; cardiac surgery;

    Sammanfattning : Background: There is a high risk of bleeding complications in cardiac surgery. Fibrinogen and platelet concentrates are often used to treat perioperative bleeding, but there is little information about its efficacy. LÄS MER