Sökning: "pattern recognition proteins"

Visar resultat 26 - 30 av 49 avhandlingar innehållade orden pattern recognition proteins.

  1. 26. Analysis of Complex Biological Samples using Liquid Chromatography-Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

    Författare :Margareta Ramström; Jonas Bergquist; Per Håkansson; Karin Markides; Carol Robinson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; mass spectrometry; liquid chromatography; protein; proteomics; peptide; Fourier transform ion cyclotron resonance mass spectrometry; cerebrospinal fluid; amyotrophic lateral sclerosis; electrospray ionization; electron capture dissociation; Analytisk kemi; Analytical chemistry; Analytisk kemi;

    Sammanfattning : Studies of protein and peptide expression are vital in order to understand complex biological systems. As demonstrated in this thesis, on-line packed capillary liquid chromatography-Fourier transform ion cyclotron resonance mass spectrometry (LC-FTICR MS) is a useful analytical tool for such studies. LÄS MER

  3. 27. Structural insights into protein-protein interactions governing regulation in transcription initiation and ubiquitination

    Författare :Madhanagopal Anandapadamanaban; Maria Sunnerhagen; Martin Moche; Marie Wahren-Herlenius; Cynthia Wolberger; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Virtually every aspect of the cellular processes in eukaryotes requires that the interactions between protein molecules are well coordinated in different regulatory pathways. Any protein dysfunction involved in these regulatory pathways might lead to various pathological conditions. LÄS MER

  4. 28. Biosensor surface chemistry for oriented protein immobilization and biochip patterning

    Författare :Emma Ericsson; Karin Enander; Sofia Svedhem; Linköpings universitet; []
    Nyckelord :Biochip; biosensor; hydrogel; ligand; orientation; patterning; photochemistry; protein immobilization; surface chemistry; self-assembled monolayer; SAM;

    Sammanfattning : This licentiate thesis is focused on two methods for protein immobilization to biosensor surfaces for future applications in protein microarray formats. The common denominator is a surface chemistry based on a gold substrate with a self-assembled monolayer (SAM) of functionalized alkanethiolates. LÄS MER

  5. 29. Development of MHC class I African alleles and ex vivo detection of M.tuberculosis-reactive CD8+ T-cells

    Författare :Rebecca Axelsson Robertson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The T-cell mediated adaptive immune response is important in controlling infection with Mycobacterium tuberculosis (M.tb). Several types of T-cells participate in the anti-M.tb defense, including CD4+ and CD8+ cells. LÄS MER

  7. 30. Heparan Sulfate and Development : A Study of NDST Deficient Mice and Embryonic Stem Cells

    Författare :Katarina Holmborn; Lena Kjellén; Erik Forsberg; Catherine L. Merry; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell and molecular biology; heparan sulfate; proteoglycan; biosynthesis; N-deacetylase N-sulfotransferase; NDST; gene targeting; embryonic development; lung development; mast cells; Cell- och molekylärbiologi;

    Sammanfattning : Heparan sulfate (HS) proteoglycans consist of sulfated HS chains covalently bound to core proteins. They are ubiquitously expressed, on the cell surface and in the extracellular matrix, throughout the body. LÄS MER