Sökning: "pattern recognition proteins"

Visar resultat 16 - 20 av 49 avhandlingar innehållade orden pattern recognition proteins.

1. 16. Revisiting dental caries as an immunodeficiency disorder

   Författare :Nongfei Sheng; Nicklas Strömberg; Anders Esberg; Thomas Boren; Anna Westerlund; Vuokko Loimaranta; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; caries; immunodeficiency; proline-rich proteins; DMBT1; S. mutans; adhesin; SpaP; Cnm; Cbm; collagen binding; caries risk stratification; precision dentistry;

   Sammanfattning : Worldwide, dental caries is the major human chronic disease, with billions of people affected in terms of life quality impairment and high society costs that consumes 5-10% of the global healthcare budget. In Western countries dental caries has declined dramatically, with a trajectory of 15% high-risk individuals with recurrent caries and a non-responder behavior to standard prevention. LÄS MER

3. 17. Molecular Studies of Three Coliphage Repressor Proteins P2 C, P2 Hy dis C and Wphi C : Kinetics, Oligomeric States and Structural Studies

   Författare :Petri Henriksson Peltola; Elisabeth Haggård-Ljungquist; Sankar Adhya; Stockholms universitet; []
   Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; molekylärgenetik; Molecular Genetics;

   Sammanfattning : P2, P2 Hy dis and WΦ are heteroimmune and closely related E. coli phages that can either grow lytically or form lysogeny after infection. The developmental switch region that contains two divergent promoters, the early Pe and the lysogenic Pc promoter, and two repressors, controls the life mode of the phage. LÄS MER

4. 18. Free Fatty Acid Receptor 2 - A G protein coupled receptor with unique signaling properties in neutrophils

   Författare :Simon Lind; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neutrophils; G protein coupled receptors; Free Fatty Acid Receptor 2; GPR43; Allosteric modulation; Transactivation; Cross-talk; Biased signalling; Functional selectivity;

   Sammanfattning : The overall aim of the PhD thesis was to determine the role of neutrophil pattern recognition receptors in the initiation and resolution of inflammatory processes. Neutrophil pattern recognition receptors such as the formyl peptide receptors (FPRs) and the short free fatty acid receptors (FFARs) belong to the family of G protein coupled receptors (GPCR). LÄS MER

5. 19. Image analysis of prostate cancer tissue biomarkers

   Författare :Giuseppe Lippolis; Malmö Urologisk cancerforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; image analysis; Time Resolved Fluorescence; automated Gleason; PSA; AR; fusion gene; TMAs;

   Sammanfattning : Prostate cancer is the second most common cancer in men. In order to improve diagnosis and prognosis, new sensitive and specific biomarkers are needed. Tissue biomarkers carry expression and morphological information of the tissue where they are expressed. LÄS MER

7. 20. Ligation-mediated Molecular Analysis of Influenza Subtypes, Splicing and Protein Glycosylation

   Författare :Tim Conze; Ulf Landegren; Mats Nilsson; Ola Söderberg; Jörn Glökler; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ligase; proximity ligation; gastric cancer; glycosylation; alternative splicing; avian influenza; padlock probe; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Molekylär medicin; Molecular Medicine;

   Sammanfattning : Binder-based assays are employed throughout the life sciences. Powerful signal amplification techniques have enabled detection of very rare molecule species diluted in simple buffers. Unspecific binding of primary binders leads to increased background in more complex samples. LÄS MER