Sökning: "biosensor"

Visar resultat 1 - 5 av 186 avhandlingar innehållade ordet biosensor.

  1. 1. Revealing Secrets of Synaptic Protein Interactions A Biosensor based Strategy

    Författare :Christian Seeger; U Helena Danielson; Sarah Lummis; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surface plasmon resonance; biosensor; AMPA receptor; GABAA receptor; ligand-gated ion channel; A-kinase anchoring protein; caldendrin; calmodulin; HIV; fragment based drug discovery; Biokemi; Biochemistry; Neuroscience; Neurovetenskap;

    Sammanfattning : Protein interactions are the basis of synaptic function, and studying these interactions on a molecular level is crucial for understanding basic brain function, as well as mechanisms underlying neurological disorders. In this thesis, kinetic and mechanistic characterization of synaptic protein interactions was performed by using surface plasmon resonance biosensor technology. LÄS MER

  2. 2. Biosensor technology applied to hybridization analysis and mutation detection

    Detta är en avhandling från Stockholm : KTH

    Författare :Peter Nilsson; [1998]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; biosensor; genosensor; surface plasmon resonance; hybridization; nucleic acids; oligonucleotide; mutation detection; mismatch discrimination; modular; TECHNOLOGY Bioengineering; TEKNIKVETENSKAP Bioteknik;

    Sammanfattning : This thesis demonstrates the application of biosensor technology for molecular biology investigations, utilizing a surface plasmon resonance based optical device for mass sensitive detection of biomolecular interactions at a chipsurface. Oligonucleotide model systems were designed for analysis of the action of DNA manipulating enzymes. LÄS MER

  3. 3. Biosensor surface chemistry for oriented protein immobilization and biochip patterning

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Emma Ericsson; Karin Enander; Sofia Svedhem; [2013]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biochip; biosensor; hydrogel; ligand; orientation; patterning; photochemistry; protein immobilization; surface chemistry; self-assembled monolayer; SAM;

    Sammanfattning : This licentiate thesis is focused on two methods for protein immobilization to biosensor surfaces for future applications in protein microarray formats. The common denominator is a surface chemistry based on a gold substrate with a self-assembled monolayer (SAM) of functionalized alkanethiolates. LÄS MER

  4. 4. Affinity biosensors based on a capacitive transducer

    Detta är en avhandling från Christine Berggren, Iliongränd 11, 224 72 Lund, Sweden

    Författare :Christine Berggren; [1998]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; self-assembled monolayers; capacitance; heavy metal ion; non-labeled; nucleic acid; DNA biosensor; Biosensor; immunosensor; Analytical chemistry; Analytisk kemi;

    Sammanfattning : Capacitive biosensors were developed for several analytes such as hormones, interleukines, viruses and heavy metal ions. The sensing surfaces were prepared by immobilizing the biorecognition element to self-assembled monolayers (SAMs) on gold. SAMs form spontaneously on gold by adsorption of thiols, sulfides or disulfides. LÄS MER

  5. 5. Insights into weak affinity antibody-antigen interactionsStudies using affinity chromatography and optical biosensor

    Detta är en avhandling från Magnus Strandh, Department of Chemistry and Biomedical Sciences, University of Kalmar, SE-391 82 Kalmar, Sweden

    Författare :Magnus Strandh; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bioteknik; Biotechnology; immunosensor; biosensor; weak affinity chromatography; cross-reactivity; antibody-antigen interaction; weak affinity; biomolecular recognition; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : Molecular recognition and interaction is fundamental for the function of biological systems. The properties of the interacting biomolecules dictate the type of forces involved and the strength and dynamics of the interaction. Many interactions are very strong whereas others exhibit weak affinity. LÄS MER