Sökning: "oesophageal cancer"

Visar resultat 1 - 5 av 41 avhandlingar innehållade orden oesophageal cancer.

1. 1. Oesophageal Cancer – Novel Targets for Therapy : With focus on Hsp90, EGFR, LRIG, microtubule and telomerase

   Författare :Xuping Wu; Simon Ekman; Johan Lennartsson; Ylva Pausson-Karlsson; Michael Bergqvist; Joachim Gullbo; Stefan Bergstöm; Gunilla Enblad; Claes Mercke; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hsp90; EGFR; LRIG; microtubule; telomerase; oesophageal cancer; imetelstat; DNA double-strand break; 17-AAG; radiation; prognosis; radiosensitisation; microtubule targeting agents; Oncology; Onkologi; Oncology; Onkologi;

   Sammanfattning : Oesophageal cancer is a malignant and aggressive disease with very poor survival. The aim of this thesis was to evaluate novel therapeutic targets in oesophageal cancer. In paper I, Hsp90 was expressed in all 81 oesophageal cancer tissues and also in nine oesophageal cancer cell lines. LÄS MER

3. 2. Comparative treatment planning in external radiotherapy of malignant tumours : Potential gains using protons

   Författare :Ulf Isacsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Breast cancer; comparative treatment; Ewing sarcoma; oesophageal cancer; protontherapy; radiotherapy; rectal cancer; treatment planning algorithms; Onkologi; Oncology; Onkologi; Oncology; onkologi;

   Sammanfattning : It is well known that protons have physical characteristics superior to conventional radiation qualities in external beam radiotherapy. The primary aim of this work is to determine if the physical advantages also may lead to clinical advantages. LÄS MER

4. 3. Oesophageal and Gastric Cancer. Aspects on treatment strategies, outcome after surgery and prognostic biomarkers

   Författare :Martin Jeremiasen; Lund Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; matstrupscancer; magsäckscancer; kvalitetsregister; gastroesofageala övergången; tumörassocierade makrofager; oesophageal cancer; gastric cancer; quality register; gastroesophageal junction; tumour associated macrophages;

   Sammanfattning : .... LÄS MER

5. 4. A high-throughput pathology approach for further insight into the role of RBM3 as a biomarker of prognosis and chemotherapy response in human cancer

   Författare :Liv Ben Dror; Tumörmikromiljö; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Cancer incidence is increasing and it is the number one cause of death worldwide. Cancer is a highly heterogeneous disease and there is a great need for new early diagnostic, prognostic and treatment predictive biomarkers in order to improve patient outcomes. LÄS MER

7. 5. Symptoms, problems and care needs among patients newly diagnosed with oesophageal and gastric cancer. Implications for early palliative care

   Författare :Karin Dalhammar; Palliativt Utvecklingscentrum; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Palliative care; Oesophageal cancer; Gastric cancer; Symptoms; Problems; Care needs; Newly diagnosed; Treatment strategy;

   Sammanfattning : Background: Patients with oesophageal and gastric cancer face a poor prognosis and multiple symptoms and problems that negatively affect their quality of life. In view of the prognosis and extensive illness burden, an early palliative care approach is of importance. LÄS MER