Sökning: "nt-3"

Visar resultat 11 - 15 av 40 avhandlingar innehållade ordet nt-3.

  1. 11. Effects of neonatal handling and enriched environment on neurotrophins and cognitive function

    Författare :Therese M Pham; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Postnatal handling; Postnatal nonhandling; Enriched environment; Isolated environment; Neurotrophins; Behaviour; Rat;

    Sammanfattning : Environmental stimulation plays a critical role in the development and maintenance of behaviours and neural processes. Two experimental models that have guided research on behavioural and neural plasticity are Postnatal handling and Environmental enrichment. LÄS MER

  2. 12. Neurotrophic factors and their receptors structure-function relationships and signalling mechanisms

    Författare :Mikael Ryden; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :neurotrophins; nerve growth factor; brain-derived neurotrophic factor; neurotrophin-3; neurotrophin-4; p75 neurotrophin receptor; neuroblastoma; serinethreonine kinase receptors;

    Sammanfattning : Background: The development, survival and maintenance of the vertebrate nervous system requires the continuous supply of a set of polypeptides termed neurotrophic factors. Among these, the neurotrophins (NTs) and members of the transforming growth factor-B (TGF-B) superfamily have raised substantial hopes for future clinical applications. LÄS MER

  3. 13. A Muscle Perspective on the Pathophysiology of Amyotrophic Lateral Sclerosis : Differences between extraocular and limb muscles

    Författare :Vahid M. Harandi; Jingxia Liu; Fatima Pedrosa Domellöf; Per Stål; Fawzi Kadi; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuromuscular junctions; Extraocular muscles; Skeletal muscle; Neurotrophic factor; Wnt; Motor neuron disease; Amyotrophic lateral sclerosis; SOD1G93A mice; molekylärbiologi; Molecular Biology;

    Sammanfattning : Background: Amyotrophic lateral sclerosis (ALS) is a late-onset progressive neurodegenerative disorder. ALS has been traditionally believed to be primarily a motor neuron disease. LÄS MER

  4. 14. Neurothrophins during development : overexpression in neural stem cells

    Författare :Thomas Ringstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The neurotrophins constitute a family of secreted, diffusible peptide factors that are widely expressed in the developing nervous system. They are known to function as survival factors in the peripheral nervous system during the period of naturally occurring cell death, to promote axonal outgrowth and to affect neurotransmitter expression of responsive cells. LÄS MER

  5. 15. 12-14 week scan with emphasis on risk assessment for fetal structural malformations and fetal loss

    Författare :Maria-Dorothea Westin; gynekologisk och prenatal ultraljudsdiagnostik Obstetrisk; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet; reproduction; sexuality; Obstetrics; gynaecology; andrology; Miscarriage; Malformation; Congenital cardiac defect; Nuchal translucency; Prenatal diagnosis; Medicin människa och djur ; Medicine human and vertebrates ; Risk assessment;

    Sammanfattning : The aim was to evaluate first trimester nuchal translucency (NT) measurement for detection and risk assessment of fetal malformations and fetal loss. 39 572 pregnant women were randomised to either a routine ultrasound scan at 12-14 weeks including NT measurement or to a routine scan at 18-20 weeks. LÄS MER