Sökning: "nt-3"

Visar resultat 16 - 20 av 40 avhandlingar innehållade ordet nt-3.

  1. 16. Regulation of neurotrophins and their receptors : molecular aspects and functional implications

    Författare :Tuija Salin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :neurotrophin; nerve growth factor; brain-derived neurotrophic factor; neurotrophin-3; neurotrophin-4; glia; gliosis; neuron; tyrosine kinase receptor; transgenic; null mutation; gene; exon; intron; mRNA;

    Sammanfattning : The aim of this work was to study the regulation of neurotrophins and their receptors in a functional aspect. The studies included analysis of neuronal and glial neurotrophin gene expression, that was investigated by using molecular biological techniques. LÄS MER

  3. 17. Survival and differentiation of central noradrenergic neurons

    Författare :Pontus Holm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : About half of all central noradrenergic (NA) neurons reside in the locus coeruleus (LC). Projections from the LC reach target regions throughout the entire brain and regulate a variety of functions, such as mood, vigilance, arousal, sleep, attention and memory acquisition. LÄS MER

  4. 18. T cell production of cytokines, neurotrophins and MHC regulation in autoimmune neuroinflammation

    Författare :Saad Muhallab; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple Sclerosis (MS) is a common disabling disease of the central nervous system (CNS). A role for the major histocompatibility complex (MHC) in disease susceptibility is established but not completely understood. LÄS MER

  5. 19. Biochemical and biophysical aspects of molecular recognition and signalling by neurotrophins

    Författare :Leopold Luna Ilag; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neurotrophins are members of a family of structurally and functionally related neurotrophic factors that control the development and maintenance of the nervous system. There are currently 5 members which make up this family: nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), neurotrophin-4(NT-4) and neurotrophin-6 (NT-6), which so far is only described in fish. LÄS MER

  7. 20. Effects of Inflammatory Mediators on Pulmonary Airways

    Författare :Ofir Bachar; Klinisk och experimentell allergiforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electric ?eld stimulation; bradykinin; airway; tumor necrosis factor a; Respiratory system; nitric oxide; Andningsorganen; Toll-like receptor; prostaglandin E2; neurotrophin; allergy;

    Sammanfattning : Chronic inflammation is together with excessive contraction of the airways key features of asthma. The aims of the thesis were to analyze the effect of inflammatory mediators on airway smooth muscle, using an in vitro model of cultured murine airways. LÄS MER