Sökning: "neutralizing antibody"

Visar resultat 6 - 10 av 76 avhandlingar innehållade orden neutralizing antibody.

1. 6. Antibody- and osteoclast-dependent mechanisms of chronic pain

   Författare :Alexandra Jurczak; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Chronic pain is a frequent condition that affects approximately 20% of worldwide population with a higher prevalence among women. Due to the lack of optimal treatment, chronic pain leads to decreased life quality as well as significant physical and psychological complications. LÄS MER

3. 7. Antibody responses in Plasmodium falciparum malaria and their relation to protection against the disease

   Författare :Ahmed Kamal Bolad; Klavs Berzins; Lars Hviid; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunity; parasital immunology; Plasmodium falciparum malaria; antibody mediated invasion growth inhibition; Immunology; Immunologi;

   Sammanfattning : Protective immunity against Plasmodium falciparum may be obtained after repeated exposure to infection. Several studies indicate that immunity against the blood stages of the P. Falciparum infection is mainly antibody mediated. LÄS MER

4. 8. Serology of human papillomavirus type 16

   Författare :Xiaohong Wang; Malmö Klinisk mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; bacteriology; Microbiology; neutralization; avidity; heparin; epitope; ELISA; HPV16; antibody response;

   Sammanfattning : Human papillomavirus (HPV) type 16 is the major cause of cervical intraepithelial neoplasia and anogenital cancers. The antibody response to papillomaviruses is a key determinant of protective immunity and forms the basis for prophylactic vaccine development as well as for seroepidemiology. LÄS MER

5. 9. Expression of recombinant neutralizing anti-HIV-1 antibodies in bacteria and eukaryotic cells

   Författare :Fayezeh Yari; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Phage display; vector; monoclonal antibody; antigen; eukaryotic; prokaryotic; transfection; selection; transient expression; stable cell line; neutralizing antibody; expression; HIVA-1; gp41; gp120;

   Sammanfattning : The main purpose of this study was to investigate and optimize techniques for eukaryotic expression of antibody molecules (IgG, Fab and scFV-ê formats), derived from an immune phage displayed Fab library and reactive against HIV-1 glycoproteins gp120 and gp41. Light and heavy-chain (Fd) DNA from a number of Fab clones were transferred from a prokaryotic phagemid vectors to mammalian expression vectors. LÄS MER

7. 10. Effects of galectins and antibodies in HIV infection; Novel Assays

   Författare :Enas Sheik-Khalil; Institutionen för laboratoriemedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; galectin-1; galectin-8; neutralizing antibodies; cell-cell fusion; Microscale anisotropy assay; virus binding assay; glycosylation; gp120; Automated plaque reduction assay; CellProfiler; NeutNet;

   Sammanfattning : The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contributes to the limited host immune control. Still, broadly neutralizing antibodies (bnAbs) are found in some chronically infected HIV-infected individuals, which has spurred the research on antibody-based vaccines. LÄS MER