Sökning: "cell-cell fusion"

Hittade 5 avhandlingar innehållade orden cell-cell fusion.

1. 1. Effects of galectins and antibodies in HIV infection; Novel Assays

   Författare :Enas Sheik-Khalil; Institutionen för laboratoriemedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; galectin-1; galectin-8; neutralizing antibodies; cell-cell fusion; Microscale anisotropy assay; virus binding assay; glycosylation; gp120; Automated plaque reduction assay; CellProfiler; NeutNet;

   Sammanfattning : The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contributes to the limited host immune control. Still, broadly neutralizing antibodies (bnAbs) are found in some chronically infected HIV-infected individuals, which has spurred the research on antibody-based vaccines. LÄS MER

3. 2. Functional screening and molecular characterisation of small proteins

   Författare :Dörte Schlesinger; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Proteins are one of the main drivers of cellular function. Most known proteins constitute various hundred amino acids, but growing evidence suggests that additionally thousands of short open reading frames (sORFs) are translated, posing the exciting possibility that many small unknown proteins are yet to be discovered. LÄS MER

4. 3. SARS coronavirus : the role of accessory proteins and nitric oxide in the replication cycle

   Författare :Sara Åkerström; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Severe acute respiratory syndrome coronavirus (SARS-CoV) caused the first pandemic of the 21st century. The etiological agent was identified as a novel coronavirus. Until then, human coronaviruses (HCoVs) had only been known to cause the common cold . Data indicated that the virus originated from animals. LÄS MER

5. 4. Studies on the biosynthesis of ABH and Lewis epitopes on O-glycans

   Författare :Jonas Löfling; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Fucose; Lewis antigen; Blood group ABH; biosynthesis;

   Sammanfattning : ABH and Lewis antigens are carbohydrate epitopes (glycans) found on a wide variety of cell surfaces. They are involved in many biological processes, e.g transplantation rejection, bacterial and viral adhesion, cell-cell communication and metastasis. The in vivo synthesis of glycans is mediated by glycosyltransferases (GTs). LÄS MER

7. 5. Virus Host Interactions in SARS Coronavirus Infection

   Författare :Vithiagaran Gunalan; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The global outbreak of Severe Acute Respiratory Syndrome which began in 2002 and ended in 2003 resulted in over 8000 cases in 29 countries, causing an atypical pneumonia which resulted in a case fatality rate of ~10%. The etiological agent of this disease was found to be a novel coronavirus dubbed SARS Coronavirus (SARS-CoV). LÄS MER