Sökning: "virus binding assay"

Visar resultat 1 - 5 av 58 avhandlingar innehållade orden virus binding assay.

  1. 1. Proximity Extension Assay : a universal tool for proteomics in precision medicine

    Författare :Phathutshedzo M. Muthelo; Ulf Landegren; Jochen Schwenk; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proximity Extension Assay; Precision medicine; Assay development; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : Precision medicine aims to utilise biomarkers to ensure the right treatment is given to the right patient at the right time. In pursuit of this goal, sensitive protein detection is essential to improve opportunities for discovery, verification, validation and development of valuable protein biomarkers. LÄS MER

  3. 2. Sialic acid-dependent binding specificities of Helicobacter pylori and influenza virus. Importance of different parts of the binding sequences

    Författare :Petra Johansson; Göteborgs universitet; []
    Nyckelord :sialic acid; carbohydrates; Helicobacter pylori; influenza virus; binding specificities; glycosphingolipids;

    Sammanfattning : Many viruses and bacteria adhere to host cell glycoconjugates in a specific manner, utilizing selected carbohydrate sequences. The aim of this work was to investigate at a molecular level the interactions of two important human pathogens, influenza virus and Helicobacter pylori, with sialylated carbohydrate structures. LÄS MER

  4. 3. Effects of galectins and antibodies in HIV infection; Novel Assays

    Författare :Enas Sheik-Khalil; Institutionen för laboratoriemedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; galectin-1; galectin-8; neutralizing antibodies; cell-cell fusion; Microscale anisotropy assay; virus binding assay; glycosylation; gp120; Automated plaque reduction assay; CellProfiler; NeutNet;

    Sammanfattning : The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contributes to the limited host immune control. Still, broadly neutralizing antibodies (bnAbs) are found in some chronically infected HIV-infected individuals, which has spurred the research on antibody-based vaccines. LÄS MER

  5. 4. Rift Valley fever : consequences of virus-host interactions

    Författare :Maria Baudin; Magnus Evander; Clas Ahlm; Göran Bucht; Tomas Bergström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rift Valley fever; Rift Valley fever virus; viral haemorrhagic fever; miscarriage; entry; charge; carbohydrates; high-throughput screening; antiviral; cell-based assay; medicinsk virologi; Medical Virology;

    Sammanfattning : Rift Valley fever virus (RVFV) is a mosquito-borne virus which has the ability to infect a large variety of animals including humans in Africa and Arabian Peninsula. The abortion rate among these animals are close to 100%, and young animals develop severe disease which often are lethal. LÄS MER

  7. 5. Mechanisms involved in adenovirus binding to and infection of host cells

    Författare :Cecilia Nyberg; Niklas Arnberg; Pierre Boulanger; Umeå universitet; []
    Nyckelord :Adenovirus; binding; infection; lactoferrin; coagulation factor IX and X; fiber; MEDICINE; MEDICIN;

    Sammanfattning : The adenovirus (Ad) family consists of 52 different human types, which are divided into seven species (A-G). Human Ads cause disease in the respiratory tract, lymphoid tissue, intestine, urinary tract, and/or in the eye. LÄS MER