Sökning: "transient expression"

Visar resultat 1 - 5 av 270 avhandlingar innehållade orden transient expression.

  1. 1. Gene and protein expression in denervated atrophic and hypertrophic skeletal muscle

    Författare :Marlene Norrby; Sven Tågerud; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Skeletal muscle; Denervation; Hypertrophy; Atrophy; Gene expression; Protein expression; Protein phosphorylation; NIFK; Wnt; MK2; Akt signaling;

    Sammanfattning : Following denervation skeletal muscles change their functional and structural properties. Some changes resemble conditions in developing muscles and may be important for reinnervation. Due to inactivity following denervation most skeletal muscles loose muscle mass and become atrophic. LÄS MER

  2. 2. Design, expression, and analysis of antibody-based blood-brain barrier shuttles

    Författare :Andrés de la Rosa; Greta Hultqvist; Paul O'Callaghan; Nicole G. Metzendorf; Torben Moos; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibody therapeutics; transient gene expression; protein production; blood-brain barri-er BBB ; BBB shuttle; brain delivery; Transferrin receptor TfR ; heparan sulfate; holo-transferrin; Molekylär biovetenskap; Molecular Life Sciences;

    Sammanfattning : Antibody therapeutics, with their strong and highly selective target binding, are now used to treat various diseases. However, to enable their use to treat brain disorders, they must be delivered across the blood-brain barrier (BBB), as without active transport, only around 0.01% of intravenously injected doses reach the brain. LÄS MER

  3. 3. Global Profiling of Host Cell Gene Expression During Adenovirus Infection

    Författare :Fredrik Granberg; Hongxing Zhao; Ulf Pettersson; Richard Roberts; Uppsala universitet; []
    Nyckelord :Genetic engineering; Adenovirus; Microarray; Gene expression; Host-virus interaction; Genteknik;

    Sammanfattning : To investigate mechanisms involved in virus-host interactions, global changes in host gene expression were examined during infection with adenovirus type 2 (Ad2) using cDNA microarray technology. In paper I and II, transcriptional changes in HeLa cells were investigated during the early and late phase of infection, respectively. LÄS MER

  4. 4. On the way of making plants smell like moths - a synthetic biology approach

    Författare :Bao-Jian Ding; Funktionell zoologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; moth pheromone; transcriptome; fatty acyl desaturase; fatty acyl reductase; acetyltransferase; chain shortening; chain elongation; heterologous expression; synthetic biology; plant expression;

    Sammanfattning : Moth caterpillars are major agricultural pests in many parts of the world. In general female moths attract male mates with their pheromone over long distance. Most of the described moth pheromones belong to the same class of chemical compounds, fatty acid derivatives that are produced de novo in the pheromone gland. LÄS MER

  5. 5. Never Heard Before: A Musical Exploration of Organ Voicing

    Författare :João Segurado; Göteborgs universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; voicing; voicing; sound; listening; pipe; organ; tone; musical composition; musical performance; experimental; collaboration; artistic research; ethnography; musique concrète; transient; attack; steady-state; ; harmonic spectrum; languid; toe-hole; mouth; flue; reed; Studio Acusticum; Gerald Woehl; Piteå;

    Sammanfattning : This study describes the role of organ sounds in musical performance and exa- mines the visions and artistic perspectives of the voicer, who creates the sounds, and the organist, who uses them in performance. Organ pipe sounds are shaped in a process of gradual transformation called voicing, to suit the practice of musical performance, and they influence that practice in significant ways. LÄS MER