Sökning: "microenvironment"
Visar resultat 36 - 40 av 376 avhandlingar innehållade ordet microenvironment.
36. Generation and investigation of neural microenvironment in health and disease
Sammanfattning : Cells in our body are under the constant influence of intrinsic and extrinsic factors that modulate their behavior. Early on, starting during the development of the organism, growth factors, nutrients, oxygen, the extracellular matrix and contact with other cells affect essential processes such as proliferation, migration, differentiation and apoptosis. LÄS MER
37. Preclinical evaluation of immunostimulatory gene therapy for pancreatic cancer
Sammanfattning : Pancreatic cancer is characterized by its desmoplastic tumor microenvironment and the infiltration of immunosuppressive cells. It is a devastating disease where most patients are diagnosed at a late stage and the treatment options are few. The development of new treatments is surly needed. LÄS MER
38. 3D Printed scaffolds as cancer microenvironment medels for drug discovery
Sammanfattning : Cancer is one of the most common diseases in the modern world and major efforts are made globally to develop new diagnostics and treatments. It originates from a cell which, at some point, has begun to divide and grow uncontrollably. The most common type is breast cancer, and like all other cancers there is a need of more efficient drug therapies. LÄS MER
39. Extracellular Matrix and Connective Tissue Cells of the Tumor Microenvironment
Sammanfattning : In addition to malignant cells, solid tumors comprise supporting stromal tissue that consists of extra cellular matrix (ECM), connective tissue cells, inflammatory cells and blood vessels. The stromal compartment and the malignant cells together shape the tumor microenvironment that in turn determines tumor progression and efficacy of anti-tumor treatments. LÄS MER
40. Immune modulation in serous epithelial ovarian cancer : focus on the role of tumor-derived exosomes
Sammanfattning : Serous epithelial ovarian cancer (EOC) is a potent suppressor of the immune defense. Here, we studied interactions between EOC and the immune system that lead to escape from tumor immune surveillance. LÄS MER