Sökning: "Tanja de Gruijl"
Hittade 2 avhandlingar innehållade orden Tanja de Gruijl.
1. Preclinical evaluation of immunostimulatory gene therapy for pancreatic cancer
Sammanfattning : Pancreatic cancer is characterized by its desmoplastic tumor microenvironment and the infiltration of immunosuppressive cells. It is a devastating disease where most patients are diagnosed at a late stage and the treatment options are few. The development of new treatments is surly needed. LÄS MER
2. Allogeneic dendritic cells as adjuvants in cancer immunotherapy
Sammanfattning : In recent years, immunotherapeutic approaches have achieved remarkable successes through checkpoint blockade antibodies, advances in the use of chimeric antigen receptor (CAR) T cells and new insights into the immunosuppressive role of the tumor microenvironment (TME). Through the advances, the role of cancer vaccines based on ex vivo manipulated autologous dendritic cells (DC) has been challenged. LÄS MER