Sökning: "ULBP"
Hittade 4 avhandlingar innehållade ordet ULBP.
1. Exosomes and the NKG2D receptor-ligand system in pregnancy and cancer : using stress for survival
Sammanfattning : Although not obvious at first sight, several parallels can be drawn between pregnancy andcancer. Many proliferative, invasive and immune tolerance mechanisms that supportnormal pregnancy are also exploited by malignancies to establish a nutrient supply andevade or edit the immune response of the host. LÄS MER
2. Immune modulation in serous epithelial ovarian cancer : focus on the role of tumor-derived exosomes
Sammanfattning : Serous epithelial ovarian cancer (EOC) is a potent suppressor of the immune defense. Here, we studied interactions between EOC and the immune system that lead to escape from tumor immune surveillance. LÄS MER
3. Expression of stimulatory and inhibitory molecules in interactions between natural killer cells neurons
Sammanfattning : Natural killer (NK) cells are important effector cells of the innate and the early induced immune defense. In the nervous system they appear early during inflammation and have been ascribed a role in clearance of certain viral infections from the brain. NK cells are regulated by multiple signals transmitted via inhibitory and stimulatory receptors. LÄS MER
4. Pro-senescence therapy by targeting MYC and its network as a strategy to combat cancer
Sammanfattning : Cancer is defined as abnormal cell proliferation with the potential of metastasis and is an increasing threat to global health as the population becomes older. Cancer is triggered by gain-of-function mutations in oncogenes and loss of function mutations in tumor suppressor genes. LÄS MER