Sökning: "ULBP"

Hittade 3 avhandlingar innehållade ordet ULBP.

  1. 1. Exosomes and the NKG2D receptor-ligand system in pregnancy and cancer using stress for survival

    Detta är en avhandling från Umeå : Umeå university

    Författare :Malin Hedlund; Umeå universitet.; [2010]
    Nyckelord :Exsosomes; NKG2D; MICA; MICB; ULBP; human placenta; trophoblast; syncytiotrophoblast; thermal stress; oxidative stress; leukemia; lymphoma; immunologi; Immunology;

    Sammanfattning : Although not obvious at first sight, several parallels can be drawn between pregnancy andcancer. Many proliferative, invasive and immune tolerance mechanisms that supportnormal pregnancy are also exploited by malignancies to establish a nutrient supply andevade or edit the immune response of the host. LÄS MER

  2. 2. Immune modulation in serous epithelial ovarian cancer focus on the role of tumor-derived exosomes

    Detta är en avhandling från Umeå : Umea University

    Författare :Alireza Labani Motlagh; Umeå universitet.; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; EOC; HGSC; exosomes; NKG2D; MICA B; ULBP; DNAM-1; PVR; nectin-2; lncRNAs; immune suppression; anti-tumor immunity; NK-cell cytotoxicity; cytokines; Th1; Th2; T regulatory response; inflammation; tumor microenvironment;

    Sammanfattning : Serous epithelial ovarian cancer (EOC) is a potent suppressor of the immune defense. Here, we studied interactions between EOC and the immune system that lead to escape from tumor immune surveillance. LÄS MER

  3. 3. Expression of stimulatory and inhibitory molecules in interactions between natural killer cells neurons

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Neuroscience

    Författare :Eva Backström; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nervous system; brain; neuron; NK cells; dorsal root ganglia; hippocampus; NKG2D; RAE 1; MULT1; nerve lesion; influenza virus; MCMV.;

    Sammanfattning : Natural killer (NK) cells are important effector cells of the innate and the early induced immune defense. In the nervous system they appear early during inflammation and have been ascribed a role in clearance of certain viral infections from the brain. NK cells are regulated by multiple signals transmitted via inhibitory and stimulatory receptors. LÄS MER