Sökning: "Emma Eriksson"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden Emma Eriksson.

  1. 1. Effects of Ubiquinone-10 on the Stability and Mechanical Properties of Lipid Membranes

    Författare :Emma K. Eriksson; Katarina Edwards; Victor Agmo Hernández; Emma Sparr; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ubiquinone-10; lipid bilayers; membrane stabilizer; liposome permeability; osmotic shock; cuvettes; solanesol; Chemistry with specialization in Physical Chemistry; Kemi med inriktning mot fysikalisk kemi;

    Sammanfattning : Ubiquinones are a group of fat-soluble molecules present in many biological membranes. The most abundant version in humans, ubiquinone-10 (Q10), plays an important role in the mitochondrial respiration chain and also functions as a powerful antioxidant. Accumulating evidence suggests that Q10 also could have other functions in the membrane. LÄS MER

  3. 2. Effects of proteasome inhibitors on chondrogenesis and linear bone growth

    Författare :Emma Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Linear bone growth occurs at the growth plate, a thin layer of cartilage between the epiphysis and metaphysis of long bones. In the growth plate, resting/stem-like chondrocytes divide and generate the highly proliferative chondrocytes, which further differentiate into the enlarged hypertrophic form before being substituted by bone, a process called endochondral ossification. LÄS MER

  4. 3. Host control of intracellular bacterial infections

    Författare :Emma Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Listeria monocytogenes; CD44; flagellin; Chlamydia pneumoniae; TLR; NOD; IFNalpha beta; IFN-gamma;

    Sammanfattning : In this thesis various immune mechanisms regulating control of infections with the intracellular bacteria Listeria monocytogenes and Chlamydia pneumoniae have been studied. These bacteria infect macrophages in which they can successfully grow. However, macrophages are potent killers of intracellular bacteria. LÄS MER

  5. 4. Preclinical evaluation of immunostimulatory gene therapy for pancreatic cancer

    Författare :Emma Eriksson; Angelica Loskog; Tanja de Gruijl; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic cancer; immunotherapy; oncolytic viruses; adenoviruses; CD40L; 4-1BBL; IL-6; tumor microenvironment; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : Pancreatic cancer is characterized by its desmoplastic tumor microenvironment and the infiltration of immunosuppressive cells. It is a devastating disease where most patients are diagnosed at a late stage and the treatment options are few. The development of new treatments is surly needed. LÄS MER

  7. 5. Towards quantitative single cell analysis using optical tweezers and microfluidics

    Författare :Emma Eriksson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Optical tweezers; holographic optical tweezers; microfluidics; lab-on-a-chip; fluorescence microscopy; spatial light modulator; single cell analysis; quantitative systems biology; GFP; Saccharomyces cerevisiae;

    Sammanfattning : Experiments on single cells have the potential to uncover information that would not be possible to obtain with traditional biological techniques, which only reflect the average behavior of a population of cells. In the averaging process, information regarding heterogeneity and cellular dynamics, that may give rise to a nondeterministic behavior at the population level, is lost. LÄS MER