Sökning: "medicin diabetes avhandling"

Visar resultat 31 - 35 av 150 avhandlingar innehållade orden medicin diabetes avhandling.

  1. 31. Melatonin receptors in pancreatic islets - Linking a genetic variant to functional phenotype

    Författare :Cecilia Nagorny; Diabetes - molekylär metabolism; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melatonin receptor; knock out mice; IVGTT; OGTT; ITT; Hyperinsulinemic clamp; MTNR1B; MT2;

    Sammanfattning : Defective insulin secretion and insulin resistance are the two hallmarks of Type 2 Diabetes (T2D). The pathophysiology of the disease is not fully understood but genetic susceptibility for the disease is a new major player in the understanding of the underlying mechanisms. LÄS MER

  3. 32. Interaction between dietary factors and genetic risk for lipoprotein traits and cardiovascular disease

    Författare :Sophie Hellstrand; Diabetes - kardiovaskulär sjukdom; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diet; polyunsaturated fatty acids; diet quality index; fatty acid desaturase; blood lipids; lipoproteins; polymorphisms; genetic risk score; gene-diet interaction; cohort; epidemiology; cardiovascular disease;

    Sammanfattning : In previous studies, a high quality diet has been associated with a reduced risk of cardiovascular disease (CVD) compared to a low diet quality, and specific “healthy” diet components, such as polyunsaturated fatty acids (PUFAs), have been hypothesized to reduce the risk of CVD. However, results from epidemiological studies have been conflicting. LÄS MER

  4. 33. Hormonal regulation of phosphodiesterase 3B in adipocytes

    Författare :Rebecka Lindh; Signaltransduktionsforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; secreting systems; diabetology; Endokrinologi; Endocrinology; caveolae localization ; phosphorylation interactions ; PDE3B adipocyte adipose tissue diabetes cAMP insulin ; lipolysis caveolin-1 ; sekretion; diabetologi;

    Sammanfattning : Insulin induced activation of the cAMP degrading enzyme phosphodiesterase (PDE) 3B in adipocytes is important for insulin mediated inhibition of lipolysis. The aim of this thesis was to contribute with knowledge on the acute activation of PDE3B in response to insulin and catecholamines in adipocytes. LÄS MER

  5. 34. Ulnar nerve entrapment at the elbow - Studies on factors influencing surgical outcome

    Författare :Ilka Anker; Malmö Handkirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ulnar nerve entrapment; simple decompression; transposition; revision surgery; electrophysiology; diabetes; nerve dislocation; outcome measures;

    Sammanfattning : .... LÄS MER

  7. 35. Microvascular effects of insulin in the skin

    Författare :Alexandra Högstedt; Simon Farnebo; Bijar Ghafouri; Erik Tesselaar; Folke Sjöberg; Sven Andersson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The microcirculation in the skin is essential for skin homeostasis. In instances of altered microvascular function, that may be the result of insulin resistance, tissue morbidity may ensue. The underlying mechanisms are however complex and not fully understood. LÄS MER