Sökning: "OGTT"
Visar resultat 1 - 5 av 41 avhandlingar innehållade ordet OGTT.
1. Metabolomics of Weight Loss and Weight Maintenance in Obese Humans
Sammanfattning : .... LÄS MER
2. Mechanism-Based Modeling of the Glucose-Insulin Regulation during Clinical Provocation Experiments
Sammanfattning : Type 2 diabetes is a complex chronic metabolic disorder characterized by hyperglycemia associated with a relative deficiency of insulin secretion and a reduced response of target tissues to insulin. Considerable efforts have been put into the development of models describing the glucose-insulin system. LÄS MER
3. Melatonin receptors in pancreatic islets - Linking a genetic variant to functional phenotype
Sammanfattning : Defective insulin secretion and insulin resistance are the two hallmarks of Type 2 Diabetes (T2D). The pathophysiology of the disease is not fully understood but genetic susceptibility for the disease is a new major player in the understanding of the underlying mechanisms. LÄS MER
4. Islet hormonal hypersecretion and metformin’s effect on islet hormonal secretion studied in vitro and in vivo
Sammanfattning : Childhood obesity has surged globally. Elevated levels of free fatty acids contribute to hyperinsulinemia, hyperproinsulinemia, and hyperglucagonemia connected with both obesity and type 2 diabetes mellitus (T2DM). Metformin has beneficial effects on islets by influencing metabolism and reducing stress-induced cell death. LÄS MER
5. Microdialysis as a tool for the management of diabetes mellitus
Sammanfattning : Diabetes complications are the result of impaired metabolic control. A continuous glucose monitoring system could be a tool to improve metabolic control. Microdialysis is a minimal invasive method for investigating tissue metabolism in-vivo and provides a novel opportunity for glucose monitoring in patients with diabetes (DM). LÄS MER