Sökning: "locomotor network"

Visar resultat 1 - 5 av 34 avhandlingar innehållade orden locomotor network.

  1. 1. Deciphering the Locomotor Network : The Role of Spinal Cord Interneurons

    Författare :Sharn Perry; Klas Kullander; Kimberly Dougherty; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Locomotion; central pattern generator; mouse; gait; recurrent inhibition; Renshaw cell; Dmrt3; Chrna2; Neuroscience; Neurovetenskap;

    Sammanfattning : In the spinal cord, an intricate neural network generates and coordinates the patterning of limb movements during locomotion. This network, known as the locomotor central pattern generator (CPG), comprises of various cell populations that together orchestrate the output of motor neurons. LÄS MER

  3. 2. Swimming with the current : Fictive locomotion reveals subtle phenotypes in the zebrafish locomotor network

    Författare :Harmen Kornelis Koning; Henrik Boije; David McLean; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; dmrt3a; wt1a; spinal cord; Mauthner cell; neural development; locomotor network; zebrafish;

    Sammanfattning : Neural networks are the functional building blocks of the central nervous system. To better understand how these networks develop and operate, we turned to the zebrafish locomotor network, with a focus on subtypes of interneurons expressing dmrt3a and wt1a. LÄS MER

  4. 3. Crossing the Midline : Locomotor Neuronal Circuitry Formation

    Författare :Fatima Memic; Klas Kullander; Avihu Klar; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CPG; CIN; neuronal network; locomotion; left-right alternation;

    Sammanfattning : Networks at various levels of the nervous system coordinate different motor patterns such as respiration, eye or hand movements and locomotion. Intrinsic rhythm-generating networks that are located in the spinal cord generate motor behaviors that underlie locomotion in vertebrates. LÄS MER

  5. 4. Diving into the zebrafish locomotor network : A study on dI6 interneurons

    Författare :Ana Belen Iglesias Gonzalez; Henrik Boije; Filippo Del Bene; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; danio rerio; locomotion; dmrt3a; wt1a; calretinin; transcriptome; spinal cord; morphology; dI6 neurons; knock-down out; Neuroscience; Neurovetenskap;

    Sammanfattning : The generation and coordination of locomotion comprise of inhibitory and excitatory interneurons that govern motor neuron output to muscles. This neuronal network is known as the central pattern generator (CPG). Spinal inhibitory interneurons that originate from the dI6 population play a crucial role in the coordination of locomotor output. LÄS MER

  7. 5. Studies of Spinal Motor Control Networks in Genetically Modified Mouse Models

    Författare :Henrik Gezelius; Klas Kullander; Ted Ebendal; Martyn Goulding; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acetyl choline; central nervous system; central pattern generator; Cre recombinase; development; genetic screen; glutamate; interneuron; motor neuron; mouse; mouse genetics; movement; network; neuronal network; nicotinic receptors; physiology; Renshaw cell; rhythm; spinal cord; transmitter; Neuroscience; Neurovetenskap; Neurobiology; Neurobiologi; Molecular neurobiology; Molekylär neurobiologi; Neurophysiology; Neurofysiologi; Neurobiology; Neurobiologi; medicinsk utvecklings- och neurobiologi; Developmental Neurosciences;

    Sammanfattning : Spinal neurons are important in several aspects motor control. For example, the neurons essential for locomotor movements reside in the ventral spinal cord. In this thesis, different motor control functions are being related to neuronal populations defined by their common expression of a gene. LÄS MER