Sökning: "Retrograde labelling"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Retrograde labelling.

  1. 1. End-to-side nerve repair - A study in the forelimb of the rat

    Författare :Eleana Bontioti; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nerve regeneration; Kirurgi; traumatology; Surgery; orthopaedics; Medicin människa och djur ; Medicine human and vertebrates ; Retrograde labelling; ATF3; Collateral sprouting; ortopedi; traumatologi; Nerve injury;

    Sammanfattning : Nerve injuries have a profound impact on individuals, suffering for the patients and induce cost for society. When dealing with severe nerve injuries that create a gap between nerve segments or when the injury is at the brachial plexus level, the clinical alternatives are limited. LÄS MER

  3. 2. In vivo properties of neural stem cells after transplantation into the rat brain-Studies of phenotypic differentiation and functional integration using cell-specific labelling and electrophysiological techniques

    Författare :Ulrica Englund Johansson; Peter Eriksson; Lund Oftalmologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell line; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; functional integration; electrophysiology; retrograde tracing; immortalized; GFP; migration; axonal projections; glia; neuron; transplantation; stem cell. progenitor cell; CNS; Biomedical Sciences;

    Sammanfattning : In the present thesis, we have examined the in vivo properties of in vitro expanded human and rat neural stem-and progenitor cells after transplantation into the neonatal and adult rat brain. The survival and differentiation of the grafted cells were assessed using species-specific antisera, and pre-labelling with the reporter gene green fluorescent protein (GFP). LÄS MER

  4. 3. Brain Stem Involvement in Immune and Aversive Challenge

    Författare :Jakob Paues; Anders Blomqvist; Finn Hallböök; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lipopolysaccharide; Lithium Chloride; anorexia; aversion; parabrachial; brain stem; melanocortin; CGRP; enkephalin; Neurobiology; Neurobiologi;

    Sammanfattning : Activation of the immune system by e.g. bacteria induces the acute-phase-response and sickness behaviour. The latter encompasses among other things fever, lethargy, anorexia and hyperalgesia. LÄS MER

  5. 4. Zinc-enriched neurons in the spinal cord, cerebellum and peripheral sympathetic system

    Författare :Zhan-You Wang; Göteborgs universitet; []
    Nyckelord :autometallography; axonal transport; confocal laser scanning microscopy; immuno-electron microscopy; immunofluorescence; inhibitory neurons; sympathetic neurons; synaptic vesicles; zinc ions; zinc transporter;

    Sammanfattning : Zinc ions are abundant in the nervous system and are involved in many biological functions. Most zinc is tightly bound to macromolecules, whereas a small fraction of zinc exists in synaptic vesicles of the zinc-enriched (ZEN) neurons, and can be visualized using various histochemical techniques, including autometallography (AMG). LÄS MER

  7. 5. Nerve gap repair by the use of artificial conduits and cultured cells

    Författare :Daniel Kalbermatten; Mikael Wiberg; Ulrich Mennen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose stem cells; cell matrix; fibrin; nerve conduit; nerve gap; Surgery; Kirurgi; kirurgi; Surgery;

    Sammanfattning : Peripheral nerve injuries are often associated with loss of nerve tissue and require autologous nerve grafts to provide a physical substrate for axonal growth. This thesis investigates the use of fibrin as both a tubular conduit to guide nerve regeneration and also as a matrix material to suspend various regenerative cell types within/on poly-3-hydroxybutyrate (PHB) nerve conduits. LÄS MER