Sökning: "klinisk farmakologi"

Visar resultat 11 - 15 av 317 avhandlingar innehållade orden klinisk farmakologi.

  1. 11. The cellular processing of the endocannabinoid anandamide and its pharmacological manipulation

    Detta är en avhandling från Umeå : Farmakologi och klinisk neurovetenskap

    Författare :Lina Thors; Umeå universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocannabinoid; anandamide; cellular processing; pain; flavonoids; fatty acid amide hydrolase; MEDICINE Physiology and pharmacology Pharmacological research Pharmacology; MEDICIN Fysiologi och farmakologi Farmakologisk forskning Farmakologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Anandamide (arachidonoyl ethanolamide, AEA) and 2-arachidonoyl glycerol (2-AG) exert most of their actions by binding to cannabinoid receptors. The effects of the endocannabinoids are short-lived due to rapid cellular accumulation and metabolism, for AEA, primarily by the enzymes fatty acid amide hydrolase (FAAH). LÄS MER

  2. 12. Behavioral effects of female sex steroid hormones models of PMS and PMDD in Wistar rats

    Detta är en avhandling från Umaå : Department of Clinical Sciences, Division of Obstetrics and Gynecology

    Författare :Magnus Löfgren; Umeå universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; PMS; PMDD; rats; progesterone; estradiol; behavior; individual response; stress interaction; tolerance; withdrawal; learning and memory; anxiety.; PHARMACY Biological research on drug dependence; FARMACI Biologisk beroendeforskning; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Endocrinology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Endokrinologi; MEDICINE Surgery Obstetrics and women s diseases Obstetrics and gynaecology; MEDICIN Kirurgi Obstetrik och kvinnosjukdomar Obstetrik och gynekologi; MEDICINE Physiology and pharmacology Pharmacological research; MEDICIN Fysiologi och farmakologi Farmakologisk forskning; VETERINARY MEDICINE Obstetrics and gynaecology; VETERINÄRMEDICIN Obstetrik och gynekologi; SOCIAL SCIENCES Social sciences Psychology; SAMHÄLLSVETENSKAP Socialvetenskap Psykologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Background Animal models can be used to mimic human conditions of psychopathology, and also as pre-clinical models to evaluate candidate drugs. With hormonal treatment it is possible to produce behavior in the rat which corresponds to the mental symptoms of pre-menstrual syndrome (PMS), and pre-menstrual dysphoric disorder (PMDD). LÄS MER

  3. 13. Amine oxidases in dental pulp a study with special regard to a semicarbazide-sensitive amine oxidase with catalytic potency towards serotonin

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Astrid Norqvist-Sjöberg; Umeå universitet.; [1988]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The amine oxidizing capacity of piglet dental pulp tissue has been investigated. At least six separate enzyme activities could be distinguished:- a soluble semicarbazide-sensitive (SSAO) activity towards benzylamine, most likely to be derived from the content of blood plasma within the pulp tissue;- a soluble pulp tissue SSAO activity with most properties in common with the plasma enzyme, however with great efficiency not only regarding benzylamine but also tryptamine;- a tissue bound SSAO activity with activity towards benzylamine, tryptamine, tyramine and ß-phenylethylamine;- a tissue bound semicarbazide-sensitive activity towards serotonin (SSA0-5HT) (a combination of properties never reported before);- a mitochondrially bound and clorgyline-sensitive monoamine oxidase-A (MAO-A) activity with activity towards serotonin;- a mitochondrially bound and deprenyl-sensitive MAO-B activity with activity towards e. LÄS MER

  4. 14. Uridine, 4-thiouridine and isomaltitol in an asthma-like model Anti-inflammatory and modulating effects

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Chamilly Evaldsson; Linköpings universitet.; Linköpings universitet.; Östergötlands Läns Landsting.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Uridine; asthma; 4-thiouridine; isomaltitol; isomalt; inflammation; eosinophilia; Sephadex; animal model; rat; PHARMACY Pharmaceutical pharmacology; FARMACI Farmaceutisk farmakologi; MEDICINE; MEDICIN; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Lung diseases; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Lungsjukdomar;

    Sammanfattning : In chronic inflammatory diseases like asthma or rheumatoid arthritis, erroneous and exaggerated accumulation of leukocytes in a tissue inadvertently causes the body harm. Several efficient anti-inflammatory drugs exist, for example corticosteroids and cyclo-oxygenase inhibitors. LÄS MER

  5. 15. Medication adherence, side effects and patient-physician interaction in hypertension

    Detta är en avhandling från Göteborg : Göteborg University

    Författare :Staffan Svensson; Göteborgs universitet.; Gothenburg University.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; patient compliance; guideline adherence; hypertension; adverse effects; communication; negotiating;

    Sammanfattning : Hypertension is an important risk factor for cardiovascular disease, the incidence of which it is possible to reduce by prophylactic treatment with antihypertensive drugs. In clinical practice, however, only a minority of patients reach target blood pressure levels. LÄS MER