Sökning: "klinisk farmakologi"

Visar resultat 16 - 20 av 191 avhandlingar innehållade orden klinisk farmakologi.

  1. 16. Vascular receptor changes in ischemic stroke

    Detta är en avhandling från Department of Clinical Sciences, Lund University

    Författare :Emelie Stenman; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vascular receptor changes; Ischemic stroke; Endothelin; Angiotensin; Cardiovascular system; Kardiovaskulära systemet; Pharmacological sciences; pharmacognosy; pharmacy; farmakognosi; farmaci; toxikologi; toxicology; Farmakologi;

    Sammanfattning : The present thesis aimed to examine how ischemic stroke affects the vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. LÄS MER

  2. 17. Disinhibitory and aggressive behavior in the rat. Neurohumoral mechanisms

    Detta är en avhandling från Göteborg

    Författare :Anders I Svensson; Göteborgs universitet.; Gothenburg University.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Effective pharmacological treatment for impulsive aggression and dysfunctional impulsive behavior is needed. These behavioral disturbences in man and impulsive-like and aggressive behavior in animals may involve serotonin (5-HT), noradrenaline (NA), GABAA receptors and steroid hormones, e.g. testosterone. LÄS MER

  3. 18. New Methods to Screen for Cancer Drugs and to Evaluate their Mechanism of Action

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Linda Rickardson; Uppsala universitet.; [2008]
    Nyckelord :Pharmacology; Cancer drugs; Screening; Gene expression; Farmakologi;

    Sammanfattning : Cancer is a common disease and due to problems with resistance against cancer drugs and the limited benefit from chemotherapy in many diagnoses, there is a need to develop new cancer drugs. In this thesis new methods to screen for cancer drugs and to evaluate their mechanism of action are discussed. LÄS MER

  4. 19. Pharmacometric Models for Individualisation of Warfarin in Adults and Children

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Anna-Karin Hamberg; Mia Wadelius; E Niclas Jonsson; Lena E Friberg; Jeffrey S Barrett; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; warfarin; pharmacokinetics; pharmacodynamics; pharmacometrics; pharmacogenetics; dose individualisation; children; Klinisk farmakologi; Clinical Pharmacology;

    Sammanfattning : Warfarin is one of the most widely used anticoagulants. Therapy is complicated by warfarin’s narrow therapeutic range and pronounced variability in individual dose requirements. Although warfarin therapy is uncommon in children, it is crucial for children with certain congenital or acquired heart diseases. LÄS MER

  5. 20. Neuropeptide Receptors as Treatment Targets in Alcohol Use Disorders

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Abdul Maruf Asif Aziz; Annika Thorsell; David Engblom; Elizabeth Jerlhag; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Alcohol use disorder (AUD) is a complex disorder with multiple pathophysiological processes contributing to the initiation, progression and development of the disease state. AUD is a chronic relapsing disease with escalation of alcohol-intake over time in repeated cycles of tolerance, abstinence and relapse and hence, it is very difficult to treat. LÄS MER