Sökning: "endothelin receptor antagonists"
Visar resultat 1 - 5 av 15 avhandlingar innehållade orden endothelin receptor antagonists.
- Detta är en avhandling från Laboratory of Experimental Vascular Research Department of Clinical Sciences Lund University
Sammanfattning : Endothelin-1 (ET-1) is an extremely potent smooth muscle spasmogen well known from the vascular system but also active within the airways. The importance of its proinflammatory and co-mitogenic properties has become increasingly evident, the endothelin system also having been shown to mimic the signal features of asthma, COPD and other pulmonary diseases. LÄS MER
- Detta är en avhandling från Department of Internal Medcine, University Hospital of Lund
Sammanfattning : A network of perivascular nerve fibres was demonstrated in coronary arteries and veins from guinea-pig and man. Nerve fibres displaying immunoreactivity to neuropeptide Y (NPY) had a distribution pattern similar to those containing immunoreactivity to tyrosine hydroxylase. LÄS MER
- Detta är en avhandling från Umeå : Umeå universitet
Sammanfattning : Background: Pulmonary hypertension (PH) is a rare condition characterized by endothelial dysfunction and vascular remodelling, leading to increased pulmonary vascular resistance (PVR) and right ventricular heart failure. Endothelial dysfunction is associated with an imbalance between vasoconstrictor compounds, such as endothelin and thromboxane A2, and vasodilator compounds, such as prostacyclin and nitric oxide (NO). LÄS MER
- Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Surgical Science
Sammanfattning : The endothelium-derived peptide endothelin-1, acting via the endothelinA and endothelinB receptors, possesses strong vasoconstrictive properties shown to affect pulmonary and systemic circulation as well as cardiac function. During septic and endotoxin shock a marked increase in circulating plasma endothelin-1 levels is observed which is associated with morbidity, cardiac dysfunction and lung injury. LÄS MER
5. Endothelin in the pulmonary circulation with special reference to hypoxic pulmonary vasoconstrictionDetta är en avhandling från Stockholm : Karolinska Institutet, false
Sammanfattning : Endothelin in the pulmonary circulation with special reference to hypoxic pulmonary vasoconstriction Peter Holm A number of substances originating from the pulmonary endothelium have recently been found to be involved in the regulation of pulmonary vascular tone. Accumulating evidence suggests that endothelial dysfunction contributes to pulmonary hypertension, an important clinical problem often associated with hypoxemia. LÄS MER