Sökning: "inflammation protein biomarkers"

Visar resultat 21 - 25 av 112 avhandlingar innehållade orden inflammation protein biomarkers.

  1. 21. Detecting the Vulnerable Plaque

    Författare :Andreas Edsfeldt; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; Carotid plaque; Inflammation; Diabetes; LpPLA2; suPAR; Cytokines; Lipids;

    Sammanfattning : Myocardial infarction and stroke, mainly caused by a rupture of an atherosclerotic plaque, are two of the most common causes of mortality and morbidity in the world. Previous studies have pointed out inflammation, driven by inflammatory lipids, as the keystone in the formation of the rupture prone vulnerable plaque. LÄS MER

  3. 22. The Molecular Epidemiology of Non-Small Cell Lung Cancer

    Författare :Johan Isaksson; Johan Botling; Eva Brandén; Hirsh Koyi; Aija Knuuttila; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NSCLC; Lung Cancer; Epidemiology; Genetics; KRAS; Pathology; Biomarkers; Oncology; Onkologi;

    Sammanfattning : The aim of this thesis was to explore the role of a spectrum of biomarkers, for disease classification or predictors of treatment outcomes in non-small cell lung cancer (NSCLC).Paper I examined the impact of systemic inflammation on the clinical outcome of NSCLC patients. LÄS MER

  4. 23. Alzheimer's Disease: The role of alpha1-antichymotrypsin-amyloid peptide (Abeta 1-42) interaction in the pathogenesis of Alzheimer's disease

    Författare :Yongxin Sun; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofysiologi; neuropsykologi; neurophysiology; Neurologi; neuropsychology; Neurology; lipid metabolism.; inflammation; á1-antichymotrypsin; Alzheimer’s disease; amyloid-â peptide;

    Sammanfattning : Alzheimer?s disease (AD) is an age-related, irreversible brain disorder that occurs gradually and results in memory loss, behavioural and personality changes. The disease is characterized by an abnormal accumulation of amyloid-beta (Ab) peptide in the extracellular space and the protein Tau within nerve cells of certain regions of the brain. LÄS MER

  5. 24. Micro-RNA: The “Micro”-managers of cardiovascular diseases - Role of extracellular vesicles-mediated miRNAs in cardiovascular diseases

    Författare :Kreema James; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiology; molecular biology; extracelluar vesicles; Micro-RNA; Protein;

    Sammanfattning : Cardiovascular disease (CVD) is the leading cause of death globally, impacted by both extrinsic and intrinsic factors. The disease at the molecular level, however, is governed by inflammation and characterized by endothelial dysfunction. LÄS MER

  7. 25. Chronic Obstructive Pulmonary Disease: Role of Alpha-1-antitrypsin

    Författare :Ruta Aldonyte; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; monocytes; inflammation; AAT polymerization; AAT; COPD;

    Sammanfattning : The only proven genetic risk factor for Chronic Obstructive Pulmonary Disease (COPD) is an inherited Z (Glu342¡úLys) deficiency of alpha-1-antitrypsin (AAT), a major inhibitor of neutrophil elastase. In vivo, AAT is found in both native (inhibitory) and modified (non-inhibitory) forms. LÄS MER