Sökning: "suPAR"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet suPAR.

  1. 1. The uPA receptor in ovarian cancer. Regulation by EGF and the estrogen responsive membrane receptor GPR30. Soluble uPAR in diagnosis and prognosis

    Författare :Emir Henic; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; G-1.; GPR30; suPAR; prognosis; estradiol; ovarian cancer; EGFR; ER; diagnosis;

    Sammanfattning : Cell migration is the first step of the invasive process, which is part of the malignant phenotype, and the uPA receptor (uPAR) plays a central role in cell migration. We studied the role of EGF and estrogen on cell migration and uPAR expression in ovarian cancer cell lines. LÄS MER

  3. 2. Detecting the Vulnerable Plaque

    Författare :Andreas Edsfeldt; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; Carotid plaque; Inflammation; Diabetes; LpPLA2; suPAR; Cytokines; Lipids;

    Sammanfattning : Myocardial infarction and stroke, mainly caused by a rupture of an atherosclerotic plaque, are two of the most common causes of mortality and morbidity in the world. Previous studies have pointed out inflammation, driven by inflammatory lipids, as the keystone in the formation of the rupture prone vulnerable plaque. LÄS MER

  4. 3. Biomarkers and mediators in systemic lupus erythematosus : IFNα versus the CRP response, and evaluation of suPAR and anti-dsDNA antibody assays

    Författare :Helena Enocsson; Jonas Wetterö; Thomas Skogh; Christopher Sjöwall; Søren Jacobsen; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease which may affect multiple organ systems. Interferon alpha (IFNα) and autoantibodies that form immune complexes with nuclear antigens (ANA) are hallmarks believed to drive the disease into a vicious circle of inflammation, tissue damage, autoantigen exposure and autoantibody production. LÄS MER

  5. 4. Rectal Cancer - Tumor Biology and Prognostic Markers

    Författare :Eva Fernebro; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prognostic markers; Cytology; oncology; cancerology; Cytologi; onkologi; cancer; immunohistochemistry IHC ; chromosomal instability CIN ; microsatellite instability MSI ; tissue microarray TMA ; tissue inhibitor of metalloproteinase 1 TIMP-1 ; Rectal cancer; soluble urokinase plasminogen activator receptor suPAR ;

    Sammanfattning : Colorectal cancer is one of our most common malignancies and the second leading cause of cancer death worldwide. About 1/3 of the tumors are located in the rectum. LÄS MER

  7. 5. Aspects on sepsis : treatment and markers

    Författare :Anna Gustafsson; Malmö högskola; []
    Nyckelord :antimicrobial peptides; cytokines; lipoteichoic acid; lipopolysaccharide; soluble urokinase plasminogen activator receptor; sepsis;

    Sammanfattning : Sepsis is one of the greatest challenges in critical care medicine today, while the treatment of sepsis and evaluation of its severity is complicated. The first part of this thesis presents two approaches on the use of antimicrobial peptides in sepsis treatment, relying on both soluble and immobilized peptides. LÄS MER