Sökning: "immunosuppression"

Visar resultat 16 - 20 av 172 avhandlingar innehållade ordet immunosuppression.

  1. 16. Discordant Neural Xenografting: Analysis and Modulation of Immune Responses

    Författare :Lena Cecilia Larsson; Neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; Neurologi; neurofysiologi; neurophysiology; neuropsychology; Neurology; immunosuppression; immunology; xenograft; pig; Parkinson s disease; intracerebral transplantation;

    Sammanfattning : Transplantation of embryonic human neural tissue can restore function in patients with Parkinson’s disease, but there is a severe shortage of donor tissue which limits the applicability of the technique. Embryonic neural tissue from other species, xenogeneic tissue, would provide a readily accessible donor tissue with the potential to help patients if the immunological reactions in the host could be prevented. LÄS MER

  3. 17. Immune cells in pregnant uterine mucosa : functional properties, cellular composition and tissue organization

    Författare :Lucia Mincheva-Nilsson; Sten Hammarström; Rolf Kiessling; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunologically privileged site; TCR γδ cells; CD56 cells; large granular lymphocytes; immunosuppression; cytokine; interleukin; lymphoid cell cluster; intraepithelial lymphocytes; glandular epithelium; immuno electron microscopy; pregnancy; decidua; lactoferrin; lactoferrin receptor; colostrum;

    Sammanfattning : The pregnant uterus mucosa - decidua - is an "immunologically privileged" site. A semiallogeneic embryo is allowed to survive, develop, and grow while the same tissue implanted outside the uterus will be rejected. The decidua basalis, which participates in the placenta formation, is a tissue rich in lymphoid cells. LÄS MER

  4. 18. Regulatory T cells and mucosal-associated invariant T cells in colon adenocarcinomas; Phenotype and function

    Författare :Filip Ahlmanner; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colon cancer; regulatory T cells; CD39; adenosine; immune checkpoint molecules; immunosuppression; MAIT cells; cytokines; cancer-specific survival;

    Sammanfattning : In many solid cancers, and also in colon adenocarcinomas, an increased accumulation of lymphocytes is beneficial for the patient. However, tumor-infiltrating immune cells may be either pro- or anti-tumorigenic and the balance between these two counteracting forces partly determines patient outcome. LÄS MER

  5. 19. Studies of Regulatory T cells with Implications for Clinical Applications

    Författare :Marcus Bergström; Olle Korsgren; Wayne Hawthorn; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regulatory T cell; Treg; Transplantation; Immunology; Tolerance; Islet transplantation; Immunosuppression; Immunologi; Immunology;

    Sammanfattning : Regulatory T cells (Tregs) are vital for regulating immune homeostasis and for preventing immunopathology. The immunosuppressive functions of Tregs have raised hope for their potential use in clinical applications. LÄS MER

  7. 20. Neoehrlichia mikurensis in Sweden : An emerging tick-borne human pathogen

    Författare :Lisa Labbé Sandelin; Björn Olsen; Jonas Waldenström; Per-Eric Lindgren; Ivar Tjernberg; Lars Hagberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neoehrlichia; Tick-borne Infections; Transfusion-transmitted infections; Bacterial Zoonotic infections; Blood Donors; Immunosuppression; Infectious Diseases; Emerging; Blood Safety; Bird Migration; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : Neoehrlichia mikurensis is an emerging tick-borne human pathogen, causing neoehrlichiosis in immunosuppressed and immunocompetent individuals. It targets the vascular endothelium, leading to thromboembolic and vascular events, but can also pass without symptoms. LÄS MER