Sökning: "heme iron"

Visar resultat 21 - 25 av 47 avhandlingar innehållade orden heme iron.

  1. 21. Theoretical Studies of Cytochrome P450

    Författare :Patrik Rydberg; Beräkningskemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; quantum chemistry; Proteins; enzymology; Proteiner; enzymologi; Theoretical chemistry; transition-state force field; peroxidase; theoretical chemistry; molecular dynamics; density functional theory; cytochrome P450; porphyrin; haem; heme; kvantkemi; Teoretisk kemi;

    Sammanfattning : The cytochromes P450 are a large enzyme family that is found in all living organisms and takes part in both endogenous and exogenous metabolism. They are primarily mono-oxygenases and perform a wide range of reactions. LÄS MER

  3. 22. Assembly and Function of Nitric Oxide Reductase from Paracoccus denitrificans

    Författare :Maximilian Kahle; Pia Ädelroth; Hans-Georg Koch; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; non-heme iron; cofactor; heme-copper oxidase; AAA ; cNOR; chaperone; metal ion insertion; MoxR; nor accessory genes; FeB; liposomes; membrane mimetics; nanodiscs; reconstitution; enzymatic mechanism; NO reduction; O2 reduction; Biochemistry; biokemi;

    Sammanfattning : Bacterial denitrification is a part of the global nitrogen cycle and comprises the stepwise reduction of nitrate to molecular nitrogen, which is released to the atmosphere. Cytochrome c-dependent nitric oxide reductase (cNOR) from Paracoccus (P.) denitrificans catalyzes the reduction of nitric oxide to nitrous oxide and water. LÄS MER

  4. 23. Proton pathways in energy conversion : K-pathway analogs in O2- and NO-reductases

    Författare :Nathalie Gonska; Pia Ädelroth; Alessandro Giuffré; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; heme-copper oxidase; cytochrome c oxidase; membrane protein; respiration; electron transfer; proton transfer; redox reaction; metalloprotein; non-heme iron; cytochrome ba3; flow-flash; carbon monoxide; liposome; respiratory control ratio; Biochemistry; biokemi;

    Sammanfattning : Oxygen and nitric oxide reductases are enzymes found in aerobic and anaerobic respiration, respectively. Both enzyme groups belong to the superfamily of Heme-Copper Oxidases, which is further divided into several subgroups: oxygen-reducing enzymes into A-, B- and C-type and nitric oxide reductases into qNORs and cNORs. LÄS MER

  5. 24. Structure and mechanism of iron and magnesium chelatases - at the heme-chlorophyll branch-point

    Författare :Michel Fodje; Lunds universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biophysics; pi-helix; secondary structure; AAA; porphyrin metallation; chelatase; Molekylär biofysik;

    Sammanfattning : Tetrapyrroles are synthesised through a single branched biosynthetic pathway. Heme and chlorophyll are synthesised from the common intermediate protoporphyrin IX at the heme-chlorophyll branch-point. LÄS MER

  7. 25. Redox Reactions of NO and O2 in Iron Enzymes : A Density Functional Theory Study

    Författare :Mattias Blomberg; Per Siegbahn; Adrian Mulholland; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; enzyme catalysis; redox reactions; cytochrome oxidase; nitric oxide reductase; hyponitrous acid anhydride; peroxynitrite; myoglobin; prostaglandin synthase; PGHS; NO; N2O; O2; CO; Chemical physics; Kemisk fysik;

    Sammanfattning : In the present thesis the density functional B3LYP has been used to study reactions of NO and O2 in redox active enzymes.Reduction of nitric oxide (NO) to nitrous oxide (N2O) is an important part in the bacterial energy conservation (denitrification). LÄS MER