Sökning: "heme iron"

Visar resultat 16 - 20 av 47 avhandlingar innehållade orden heme iron.

  1. 16. Heme Protein Biogenesis - Catalase in Enterococcus faecalis

    Författare :Michael Baureder; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Enterococcus faecalis; heme proteins; protein assembly; oxidative stress; catalase; cytochrome;

    Sammanfattning : Heme proteins form a large and diverse group of proteins which are involved in a variety of biological functions. The heme prosthetic group enables them to carry out redox reactions, transport electrons, bind gaseous molecules, and function as sensors. Despite their importance only little is generally known about heme protein biogenesis. LÄS MER

  3. 17. Oligomerization of human and bacterial frataxin : Structural and functional studies

    Författare :Mostafa Abdalkhalik; Biokemi och Strukturbiologi; []
    Nyckelord :Frataxin; Friedreich’s ataxia; iron; reactive oxiden species; protein oligomerization; SAXS; EM; cross-linking; XAFS; nano- DSF;

    Sammanfattning : Friedreich’s ataxia (FRDA) is an autosomal recessive neurodegenerative disease caused by defeciency in frataxin, a highly conserved protein central to iron homeostasis in mirochondria. The function of frataxin is related to its capability to bind, store and deliver iron to different biochemical process such as iron-sulfur cluster assembly and heme biosynthesis. LÄS MER

  4. 18. Synthesis of hemes found in heme-copper oxidases of Bacillus subtilis

    Författare :Mimmi Throne-Holst; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microbiology; Biologi; Biology; heme biosynthesis; respiratory oxidase; cytochrome; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : The last step of aerobic respiration, the reduction of dioxygen to water, is catalysed by terminal oxidases. These oxidases can be divided into two unrelated families, the heme-copper oxidases and the cytochrome bd-type oxidases. These enzymes contain two or more heme molecules as prosthetic groups. LÄS MER

  5. 19. The role of the thromboinflammatory response under hemolytic conditions : pathophysiological mechanisms and therapeutic inhibition

    Författare :Alexandra Gerogianni; Per H. Nilsson; Camilla Mohlin; Tom Eirik Mollnes; Kristina Nilsson Ekdahl; Mihály Józsi; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hemolysis; heme; thromboinflammation; biomaterials; complement inhibition; LVAD; IONPs; Biomedical Sciences; Biomedicinsk vetenskap; Immunologi; Immunology;

    Sammanfattning : In blood circulation, the complement and the coagulation cascades, together with platelets and endothelial cells form a complex network of crosstalk. When dysregulated, these interactions can lead to inflammation in combination with thrombosis (thromboinflammation) and the manifestation of pathophysiological complications. LÄS MER

  7. 20. Studies on Haemproteins of Gram-positive Bacteria - Implications as Antibacterial Drug Targets

    Författare :Peter Kjelgaard; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bacteriology; virology; mycology; Mikrobiologi; Microbiology; heme; Truncated hemoglobins; cytochrome c maturation; cytochrome bd; ResB; bakteriologi; virologi; mykologi;

    Sammanfattning : With the discovery of antibiotics, several diseases that were previously lethal is today readily cured, or so we thought. Some degree of resistance to one or several antibiotics can be found among many strains of clinical important bacteria. LÄS MER